Retinol Youth Renewal Serum

New, faster + even better! Our iconic retinol serum, now powered by 4 unique retinoids to slow the visible signs of skin aging with just 1 bottle*


  • In 7 days: Clinically proven to improve 10 visible signs of early skin aging†
  • In 14 days: 100% showed visible improvements in elasticity, firmness and radiance, 93% showed visible improvements in fine lines, wrinkles, and dark spots, and 96% agree skin looks healthier†
  • In 28 days: Skin looks 2.5 years younger* and 100% of clinical study participants showed measurable improvement in all 10 visible signs of healthy, thriving skin†


*Packaging may vary

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Murad Resurgence Natural Youth Renewal Serum in a clear bottle with a green label and silver pump, held in front of a woman in a white striped top.

Skin looks 2.5 years younger in 28 days*

Details

Inspired by the latest discoveries in skin longevity science, Retinol Youth Renewal Serum is now powered by 4x Active Retinoid Technology to address the visible signs of early skin aging: an encapsulated retinol for quick, deep, stable and targeted delivery, a gentle yet fast-acting retinol, a stabilized retinoid with barrier-nourishing omega-6, and a soothing, nourishing bio-retinoid booster to offset retinol's potential for irritation​

This true do-it-all retinol serum is clinically proven to improve the 10 visible signs of early skin aging in 7 days:† ​

• Fine lines + wrinkles
• Uneven tone ​
• Dullness ​
• Dehydration ​
• Rough texture ​
• Firmness + elasticity ​
• Discoloration ​
• Skin clarity ​
• Pore size ​
• Skin barrier resilience ​

Which skin type is it good for?
  • Oily·
  • Balanced·
  • Combination·
  • Dry
Results

Unretouched real results

In 7 days:

  • Clinically proven to improve the 10 visible signs of aging†​


In 14 days:

  • 100% showed visible improvements in elasticity and firmness†​
  • 93% showed visible improvement in fine lines and wrinkles†​
  • 100% showed visible improvement in skin texture, tone, and radiance†​
  • 93% showed visible improvements in hyperpigmentation and dark spots†​
  • 96% agree skin looks healthier†​


In 28 days:

  • Participants looked 2.5 years younger*​
  • 100% showed measurable improvement in all 10 visible signs of healthy, thriving skin†


†Fine lines + wrinkles, uneven tone, dullness, dehydration, rough texture, firmness + elasticity, discoloration, skin clarity, pore size, and skin barrier resilience. Results based on a 4-week clinical study with 30 participants
*In a 4-week clinical study participants reported looking on average 2.5 years younger with just 1 bottle

Ingredients

Expert, science-backed ingredients and patented technologies

How-To

To Use: PM

A close-up of hands holding a green and silver Murad Resurgence Facial Youth Serum bottle, with a dollop of the white cream product resting on a finger against a soft mint green background.
Step 1

Apply a thin layer of Retinol Youth Renewal Serum to face. Reduce frequency if sensitivity occurs

Close-up of a smiling woman's face with a dollop of white cream applied to her cheek.

Step 2

Gently pat Retinol Youth Renewal Eye Serum around under-eyes and lids. Warning: Avoid contact with eyes

A textured smear of off-white cream or lotion with visible ridges, placed on a soft sage green background.

Step 3

Massage Retinol Youth Renewal Night Cream evenly over face, neck and chest. Always apply an SPF in the morning

Get the facts

What makes Murad's retinol different?

Our potent-yet-gentle formula equals results that are impressive, not aggressive Learn More

Retinol myths, debunked

Get the facts about this clinically proven treatment that dermatologists swear by Learn More

Overall rating: 4.818271 / 5 from 1018 reviews.

AI Generated Review Summary

Customers appreciate the Retinol Youth Renewal Serum for its ability to visibly improve key signs of aging, such as reducing fine lines and wrinkles, and making the skin look firmer and more even-toned. The product is gentle enough for nightly use, thanks to its hydrating ingredients, and many users report a noticeable difference in their skin's appearance.

Summary topics

  • Skin Appearance (10%): Customers expressed appreciation for how this product made their skin look more youthful and hydrated without any irritation.
  • Fine Lines Reduction (11%): It was highlighted by customers that the Retinol serum effectively reduces fine lines and smooths out dark spots.
  • Facial Rejuvenation (4%): It was highlighted by customers that using this product makes their face look 10 years younger. (100% agreement)
  • Skin Feel (11%): Customers appreciated how the product made their skin feel amazing, soft, smooth, and hydrated.
  • Retinol Effectiveness (6%): Customers appreciated the retinol for its effectiveness, gentle feel, and long-lasting results.

Review topics: ["size","fragrance","irritation","issues","absorbs","improvement","weight","works","wrinkles","quality","value","price","skin","feels","packaging","difference","texture","bottle","ingredients","shipping","looks","face","spots","serum","acne","consistency","formula","lines","pores","appearance"].

Review highlights

  • "In just a few weeks, it's visibly improved my skin's texture and appearance, reducing fine lines and wrinkles."Ingkaraiym
  • "Smells nice, doesn’t irritate my skin, and makes my skin look so lovely :blush:"Tanya C.
  • "Makes my face feel wonderful and it has a great scent."Mary

Reviews

I love it

"I have already used retinol 3 bottles and I decided to continue. This is a non-irritating type, helps dark spots fade, reduce wrinkles, smooth skin, very effective. Thanks to the manufacturer Murad ."

Chi L. (5/5)

One of the best anti-aging serums on the market

"I had stopped using this serum and was trying a different one. Once I went back to using it I saw a significant difference. My skin was so much brighter to the point I was receiving compliments."

Leslie E. (5/5)

No fancy packaging- just a

"No fancy packaging- just a product THAT WORKS!!! I love this so much and see such a difference - also, it is not irritating- get it!"

Linda L. (5/5)

I love love love it.

"I love love love it. I’ve been using it for 30 years and I absolutely love what it does to my skin. I use it twice a day and it’s wonderful. !!!!"

Janet H. (5/5)

Retinol renew serum

"Work very well."

Kelly N. (5/5)

it has already taken out the old lady neck wrinkles in 2 weeks

"I used this stuff for a while , then ran out for a year and forgot. Im back to useing it and remember why I lovef it so much"

Kassandra H. (5/5)

"Love Murad!"

Claudia (5/5)

"I love all of the Retinol Youth Renewal products. The serum ia my favorite. I have received so my compliments on my skin since using Murad products."

M (5/5)

"Delivered in a timely manner. Love Murad products."

Claudia (5/5)

Great Product

"This product is very nice. It has a fine texture, is neither water-y nor greasy. The smell is mild and pleasant. It applies well on the face and gets absorbed quickly. I use this in the evening and the Vita C Glycolic serum in the morning. My skin tone has improved and the skin feels soft and smooth."

Meng Z. (5/5)

Q&A

I noticed a scent from the retinol youth renewal serum. I liked it and wanted to know what the scent is.
I am so sorry however all I know is that there is fragrance in the formula however what it is, they do not release as it is considered proprietary.
Are there eco-friendly refill options once we finish the Retinol Youth Renewal night Cream?
At this time we do not have refills but we are actively discussing this.
If I run out of the youth serum retinol eye cream, is it OK to use this face serum around my eyes while I am waiting to receive the eye serum? Or should I skip it? Thank you!
We would say that you do not want to apply it any closer than the orbital bone.
What percent retinol is used? I am using .25 now and wonder how this compares?
First let me start by stating that we disclose the percentage of an ingredient only when it is an “active ingredient” in other words, an OTC (over-the-counter), FDA (Food & Drug Administration) approved ingredient. Here at Murad, as part of our Corporate policy, we do not disclose percentages in our high performance formulations as this information is considered proprietary. What I can share with you is that Dr. Murad creates formulas based on a result not a percentage. Our products are designed to treat a specific concern within the skin, keeping in mind our Whole-Person Health approach.
I'm confused! I use the serum at night, but when do I use the night cream? They were both in the intro kit with the eye cream. Also do I use a moisturizer after?
In the evening you want to cleanse your skin and pat dry. Apply the Retinol Youth Renewal Serum, the Retinol Youth Renewal Night Cream and finally the Retinol Youth Renewal Eye Serum

Frequently Asked Questions

Retinol Youth Renewal Serum is a nighttime serum formulated to target visible signs of aging, like fine lines and wrinkles. It helps improve skin texture, firmness, and tone, while delivering retinoid actives and hydrating ingredients.​

Our previous, award-winning formula was powered by 3 retinoid technologies (Retinol Tri-Active Technology). New Retinol Youth Renewal Serum is now powered by 4x Active Retinoid Technology to address the visible signs of early skin aging.

1) an encapsulated retinol for quick, deep, stable and targeted delivery​
2) a gentle yet fast-acting retinol​
3) a stabilized retinoid with barrier-nourishing omega-6​
4) a soothing, nourishing bio-retinoid booster to offset retinol's potential for irritation​

Apply to clean, dry skin at night. Follow with a moisturizer. Always use sunscreen during the day when using retinol products.​

Yes. The formula includes added fragrance (parfum) and fragrance components.

  • 4x Active Retinoid Technology: A powerful complex of retinoids that supports gentle yet accelerated surface renewal​
  • 4 collagen amino acids and antioxidants: Syncs with hyaluronic acid to maximize hydration, while helping to protect skin's natural collagen for firmer, radiant, youthful-looking skin​
  • 4 types of hyaluronic acid: Small-to-large weights work on different levels to lock in and reinforce skin-plumping hydration, while offsetting potential dryness 

Yes, you can, To reduce the potential for irritation, especially during the first few days or weeks, introduce other retinoids or strong actives slowly and consider alternating nights or using buffering steps in your routine.

When used as directed, Retinol Youth Renewal Serum is clinically proven to show results on skin as early as 7 days, with results continuing to improve over the next 28 days. Please note that results may vary.

While retinoids can be drying for some users, we intentionally formulated Retinol Youth Renewal Serum with hydrating ingredients, such as hyaluronic acids of different molecular weights and collagen amino acids, to help replenish and lock in skin's moisture. Keeping skin hydrated during retinoid use can help offset the potential for irritation and redness.


If you're concerned about dryness, we recommend applying a moisturizer over the top of the serum. You can also introduce retinol slowly to your routine, using 2-3 nights a week on alternating nights, until your skin adjusts. 

Yes, this formula is slightly stronger than the previous formula. However, it was formulated with various types of retinoids for potent-yet-gentle results, as well as hydrating ingredients, such as hyaluronic acids of different molecular weights and collagen amino acids, to help replenish and lock in skin's moisture. Keeping skin hydrated during retinoid use can help offset the potential for irritation and redness.


​​If you used the previous formula and are concerned about sensitivity or an adjustment period, we recommend doing a patch test and introducing the serum gradually or use with a buffering moisturizer.​

Murad develops formulas with proof—not percentages—in mind. We start with clinically proven ingredients, then develop innovative technologies to enhance their efficacy. Our multi-action formulas do not just consider the symptom or target a skin concern, rather, we address the entire health of the skin.

Murad conducts its own objective and subjective testing with a panel of consumers. 30 clinical trial participants reported that using Retinol Youth Renewal Serum made their skin looked 2.5 years younger. ​

Yes.

Most people can begin using retinoids in their mid-twenties. This is when early changes in texture, tone, and collagen naturally start to show on the skin, making it the ideal time to build retinoids into a preventative, results-driven routine.

A bio-retinoid is a newer generation of retinoid alternative, usually a naturally derived compound (in this case, algae derived) that mimics the effects of traditional retinoids on the skin (like surface cell renewal and smoothing fine lines) without being a vitamin A derivative itself.

Murad's bio-retinoid is a next-generation, encapsulated bio-retinol derived from marine microalgae, designed to deliver the benefits of retinol with reduced irritation. Acting in a retinol-like manner, improves skin elasticity, and smooths fine lines, while its soothing, nourishing properties help minimize redness and sensitivity.

Murad's bio-retinol is a gentle, microalgae-derived retinol-mimic that boosts renewal with less irritation, while bakuchiol is a plant-based alternative that offers similar smoothing and firming benefits but works through different, non-retinol pathways.

Retinol Youth Renewal Serum is formulated to be gentle. However, if you have reactive skin, perform a patch test and introduce the product gradually or use with a buffering moisturizer. You can also mix equal parts of the serum with your moisturizer to buffer the retinoids and reduce the chance of irritation.

No: This product contains vitamin A. We do not recommend using this product if you are pregnant or lactating. We always advise our clients to speak with their doctor about their skincare regimen and product ingredients during their pregnancy. 

Yes, you can, but we recommend being very strategic about application of the eye masks to the eyes and the cream to the face and neck to prevent layering of the two products. As always, if you experience any sensitivity, we recommend using a non-retinoid eye treatment with Retinol Youth Renewal Serum.

Yes, you can.

Yes, you can. However, we do not recommend layering Retinol Youth Renewal Serum over Retinol Youth Renewal Eye Serum, as this may be too intense for some users.

Yes, you can. We recommend using vitamin C products during the day, and retinal/retinol products at night. Always follow with an SPF during the day.

Yes, you can! This is an incredible skincare duo: Rapid Dark Spot Correcting Serum helps target dark spots and uneven skin tone, while Retinol Youth Renewal Serum helps firm and smooth the skin. We recommend using Rapid Dark Spot Correcting Serum during the day to correct dark spots and optimize antioxidant defense against skin damage, and using Retinol Youth Renewal Serum at night. Always follow with an SPF during the day.​

We recommend using Retinol Youth Renewal Serum at night to optimize skin’s receptivity and retinol’s potency.

When used as directed, Retinol Youth Renewal Serum is clinically proven to show results on skin in 7 days, with results continuing to improve over the next 28 days.