Retinal ReSculpt Overnight Treatment

Uniquely encapsulated retinal serum that dramatically lifts and improves sagging, smooths deep-set wrinkles and increases skin elasticity

 

  • Our retinal—one of the most efficacious forms of vitamin A—is encapsulated in an exclusive delivery system for enhanced stability and targeted delivery deep within skin’s surface, allowing for 2.5x more effectiveness (vs. free retinal)—while still being gentle on skin
  • Next-gen complementary ingredients amplify retinal’s benefits: Kangaroo paw flower and olive leaf extracts help improve saggy appearance, smooth wrinkles and support resilience, while oat lipids and alpha glucan help replenish ceramides, increase moisture and soothe skin
SKU: 15410
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Pharmaceutical-inspired encapsulation for 2.5x better efficacy (vs. free retinal)

Details

Our next-gen serum features retinal—one of the most efficacious forms of vitamin A—encapsulated in a delivery system that’s adapted from technology used in pharmaceutical applications. With enhanced stability and targeted delivery deep within skin’s surface, this new treatment can create transformative results by lifting neck/jowl sagging (2 weeks), smoothing deep-set wrinkles/crepey skin (2 weeks) and increasing skin elasticity (4 weeks)—all in a nourishing formula that leaves the skin supple, soft and feeling moisturized

And perhaps best of all, we have a retinoid for anyone who wants to tackle or slow signs of aging: For visible improvement on mild-to-moderate signs of aging, trust our cult-classic Retinol Youth Renewal Serum. To amp up results and corrective benefits for advanced signs of aging, reach for Retinal ReSculpt Overnight Treatment

Which skin type is it good for?
  • Balanced·
  • Oily·
  • Dry·
  • Combination
VIDEO

With 4,000+ types of retinoids, here’s how to find the right one for you

This Harvard-trained Dermatologist breaks down the difference between retinOL and retinAL—and why knowing the difference is critical to addressing your unique aging skin concerns

Retinal ReSculpt™ Overnight Treatment B&A 1
Retinal ReSculpt™ Overnight Treatment B&A 1A
Retinal ReSculpt™ Overnight Treatment B&A 2
Retinal ReSculpt™ Overnight Treatment B&A 3
Results

Unretouched clinical results with Retinal ReSculpt Overnight Treatment:


After 2 weeks

  • Visibly lifts neck/jowl sagging
  • Visibly smooths deep-set wrinkles/crepey skin


After 4 weeks

  • Increases skin elasticity


*Results based on an 8-week clinical study with 34 participants

†Proven results reported by trial participants in a 4-week clinical study
‡vs. regular retinal, independent ex-vivo study

Ingredients

Expert, science-backed ingredients and patented technologies

RESULTS

What’s your retin-type? Use Retinol Serum for mild-to-moderate aging and Retinal ReSculpt to amp up results for advanced aging

HOW-TO

To Use: PM

Step 1

Massage Renewing Cleansing Cream over dampened face, neck and closed eyes. Rinse and pat dry.

Step 2

Apply a thin layer of Retinal ReSculpt Overnight Treatment to face and neck.

Step 3

Massage Retinol Youth Renewal Night Cream evenly over face and neck. If you experience any sensitivity, switch to a non-retinol night cream. Follow with a sunscreen during the day.

Get the Facts

RetinAL rules

With over 4,000+ types of retinoids, here's how to confidently choose the right one for you Learn More

What is skin cycling and how do you do it?

The social trend that went viral is here to stay Learn More

Overall rating: 4.793201 / 5 from 353 reviews.

AI Generated Review Summary

Customers have reported significant improvements in skin texture, fine lines, and wrinkles after using the Retinal ReSculpt Overnight Treatment. The product is praised for its effectiveness, pleasant smell, and the soft, smooth, and youthful appearance it imparts to the skin.

Summary topics

  • Skin Texture Improvement (11%): It was noted by customers that they noticed a noticeable difference in their skin texture and fine lines.
  • Fine Line Reduction (12%): Customers expressed satisfaction with the reduction of fine lines and wrinkles on their skin after using the product.
  • Skin Feel (38%): Many customers expressed appreciation for how this product made their skin feel soft, smooth, and youthful.
  • Overall Treatment Effectiveness (6%): Customers expressed appreciation for the Retinal ReSculpt Overnight Treatment, describing it as incredible and effective.
  • Product Smell (10%): Customers expressed satisfaction with the smell of the product, describing it as nice, fresh, clean, and pleasant.

Review topics: [feels, packaging, skin, issues, looks, wrinkles, texture, price, improvement, spots, face, lines, irritation, fragrance, formula, difference, bottle, glow, pores, serum, reduction, weight, appearance, treatment, neck, benefits, sensation, cream, residue, value].

Review highlights

  • "My skin looks radiant, my skin looks firm, improved dark spots and my skin has a more even skin tone, love this product." — Lorena O.
  • "My skin felt great and I noticed a visible difference after just a week of use." — Andrew D.
  • "Ever since I discovered Murad products, my skin has never looked so smoothe and vibrant at the age of 63!" — Michelle M.

Reviews

Great Serum for skincare lovers

"This serum is very nice, I have used 2 pumps every night and have seen improvements in my skin texture in a few weeks. It has a very faint fragrance, feels nice on the skin and penetrates quickly. I found my skin to look smoother and improved texture, would definitely give this a try. I did not have any irritation with the retinal. I received this product to test through Gloss Angeles for my honest review"

— Marcela R. (5/5)

Great Product!

"This is one of the first products that I have tried that actually works. I have noticeably less wrinkles and sagging skin under my chin. I was gifted this product in exchange for my honest review from Gloss Angeles. I will continue to purchase this in the future. It is a little pricy but it has lasted a long time (been using it for 4 weeks and bottle still feels full) but worth the price since it actually works."

— Lauren (5/5)

Thick and Smooth Serum

"I was gifted this product from Gloss Angeles & liked applying the serum to my neck as it felt thick yet went on smooth on my neck and chest. Tried this for four weeks but didn’t notice much of a visible difference on my neck or chest but I do like how smooth my skin feels. Will continue to try this product for another four weeks."

— Lineth H. (3/5)

Love!!!

"This is such a great neck serum! I’m a side sleeper, so I often wake up with lines on my neck and chest, and I’ve already noticed a visible improvement since using this. My skin also feels hydrated in the morning, which is a plus! I have pretty sensitive skin and can sometimes react to new products, but I haven’t experienced any irritations with this serum. I’m excited to continue using it and see even more progress over time! Thank you, Gloss Angeles Confidential, for the opportunity to test this product!"

— Heike L. (5/5)

Great neck serum!

"I was able to test this serum for 4 weeks thanks to Gloss Angeles. The serum feels luxurious upon application and absorbs quickly. I found after nightly use that my neck appeared more firm and the texture was less crepey. My tech neck wrinkles and jowls also slightly diminished. I’m excited about seeing my results with using it even longer."

— Andrea T. (5/5)

Excellent neck cream

"I have enjoyed using this neck cream even though I would've never thought to purchase it. I did tan a lot when I was younger and I do feel like this gave my neck and delicate a smoother and softer appearance when I used it & I have already recommended this to friends! I think if you’re looking for a neck serum that is going to provide results with consistent use, this is the one! In the future, I would repurchase this. I received this product as a part of Gloss Angeles confidential, thank you Gloss Angeles!"

— Disa W. (5/5)

Solid Addition to Nighttime Routine

"I got this serum for free from Gloss Angeles in exchange for an honest review, so here's my honest take after using it. First off, no complaints on smell or texture. It applies really easily and my neck actually felt soft right after putting it on, which is a nice bonus. I've been using it every night like the instructions say, followed by moisturizer. As for actual results, I did notice some of my fine lines looking a bit softer with consistent use. I'm not going to pretend this is some miracle product that erased everything overnight, because it's not. But there was a small, real difference in how smooth my skin looked and felt, and that held up the more I used it. Overall it's a solid addition to a nighttime routine if you're looking for gentle, gradual improvement rather than instant drastic change. It smells good, feels good going on, and does seem to be doing something over time."

— Jen (4/5)

Good Product Overall

"I received Murad’s Retinal ReSculpt Overnight Treatment to test as part of Gloss Angeles’ seeding program. After using it consistently, I’d give it 4/5 stars. My neck looks noticeably smoother and healthier overall, and I was especially pleased that I experienced no irritation or sensitivity. I have two visible horizontal lines on my neck—one deeper crease and one finer line. While I haven’t noticed much change in the deeper line, the finer one does appear softer and less noticeable. I wouldn’t call the results dramatic, but I’ve definitely seen an improvement in my skin’s overall texture and appearance. A solid, gentle retinal treatment that I'd recommend if you need to target and improve the neck area!"

— Paige R. (4/5)

Very subtle differences

"I got to try this product thanks to Gloss Angeles. I'm not sure if I saw a huge transformation, but I did see a subtle one. I've tried other neck creams: Skin Science V Line Jaw Defining Serum, Drmtlgy Advanced Neck Cream, Nectifim Advanced Neck Firming Cream, and StriVectin TL Advanced Tightening Neck Cream Plus. I have to say -- this is a rare instance where I have seen subtle differences, and I usually have low expectations of neck creams. The only other neck product that comes close is the Skin Science V Line Jaw Defining Serum. It might also be because this is the first time I've tried a neck cream w/retinal in it. I had zero irritation, which is nice for my sensitive skin. I plan to finish the bottle. I'm not sure, at this price point, if the difference was dramatic enough for me to keep using it. I might just use my retinal eye product and bring it down to my neck as that's more budget-friendly. I guess the best thing is to wait and see if, once I finish the bottle, if my neck doesn't look as good with other retinal products I have. If you have the means, this is worth a shot."

— Jeane W. (4/5)

"Murad products do exactly what they claim!"

— Marilyn (5/5)

Q&A

What is the difference between the Retinal ReSculpt Overnight Treatment and the Retinal ReSculpt Overnight Cream? Does one have stronger, more potent, Retinal than the other?
The primary difference is their product type and role in your skincare routine: the Murad Retinal ReSculpt Overnight Treatment is a concentrated serum formulated to correct advanced signs of aging like neck and jowl sagging, while the Murad Retinal ReSculpt Overnight Cream is a deeply hydrating moisturizer designed to re-volumize facial contours and restore hormonally aging skin. Regarding potency, neither product is officially marketed as "stronger" than the other; instead, Murad maintains a corporate policy of keeping their exact retinal percentages proprietary.
Best overnight treatment for dark spots
We would recommend the Rapid Dark Spot Correcting Serum to help address the darks spots and uneven pigmentation.
What's the difference between Retinal ReSculpt and your Youth Renewal Serum?
The short answer is: Retinal is also a retinoid and form of vitamin A. Retinol must go through 2 conversions once applied to the skin to become retinoic acid. Retinal only has to go through 1 conversion once applied to the skin. This helps the product to treat more quickly and has more benefits than traditional retinol. With enhanced stability and targeted delivery deep within skin’s surface (while being less irritating that tretinoin), this potent ingredient can create transformative results!
I have been using the Retinal Resculpt Overnight Treatment, am I able to use the Retinol Renewal Night Cream for the moisturizer? Or is that too much? Thanks in advance
You can absolutely use the Retinol Youth Renewal Night Cream after the Retinal Resculpt Overnight Treatment.
How much retinol is in Retinal Resculpt? Is it less than 1%?
Here at Murad, as part of our Corporate policy, we do not disclose percentages in our high performance formulations as this information is considered proprietary. What I can share with you is that Dr. Murad creates formulas based on a result not a percentage. Our products are designed to treat a specific concern within the skin, keeping in mind our Whole-Person Health approach.

Frequently Asked Questions

An encapsulated retinal overnight treatment designed to target sagging in the neck/jowl area, smooth deep-set wrinkles, and improve the appearance of crepey skin.

Apply retinal at night after cleansing and toning but before moisturizer. Use every other night, or use 2-3 times per week and gradually increase to nightly use as your skin builds tolerance. Apply SPF 30 or higher in the morning as retinal increases sun sensitivity.

Apply a thin layer of Retinal ReSculpt Overnight Treatment to the face and neck, focusing on areas of concern such as the jawline, neck and any crepey or wrinkled areas.

Encapsulated retinal, kangaroo paw flower extract, olive leaf extract, oat lipids, and alpha glucan.

Yes, Retinal ReSculpt Overnight Treatment contains fragrance (parfum).

It's best for people concerned with neck and jowl sagging, deep-set wrinkles, loss of elasticity, and crepey skin.

This product is not ideal for those who avoid vitamin-A derivatives. Many sensitive-skin users report good tolerance, but a patch test is recommended before regular use.

Yes, Retinal ReSculpt Overnight Treatment is suitable for all skin types, including balanced, oily, dry, and combination skin. The encapsulated retinal technology delivers potent anti-aging benefits while being gentle enough for nightly use, with added ingredients like oat lipids and alpha glucan that help replenish moisture and soothe skin.

Retinal ReSculpt Overnight Treatment uses encapsulated retinal in a pharmaceutical-inspired delivery system that delivers potent vitamin A deep within the skin's surface, making it 2.5 times more effective than free retinal. The formula works overnight to promote surface cell turnover, boost collagen production, and improve elasticity. Complementary ingredients like kangaroo paw flower and olive leaf extracts help lift sagging skin and smooth wrinkles while oat lipids replenish moisture.

While Retinal ReSculpt Overnight Treatment is formulated with encapsulated retinal and soothing ingredients for enhanced gentleness, those with sensitive or redness-prone skin should start slowly with 2-3 times per week and gradually increase frequency as tolerance builds.

Murad carefully assesses our products and ingredients to help ensure they are safe for use. Because every person and pregnancy is unique, we recommend consulting your healthcare provider if you have any questions about product use during pregnancy or lactation. Please note, this product contains retinoids, which are not recommended for use during pregnancy or while breastfeeding.