Biome-Balancing Clear & Prevent Acne Treatment Serum

Size
  • 1.0 FL. OZ.

Clear all types of breakouts—from whiteheads to hormonal—and prevent acne relapses with this breakthrough serum. Salicylic acid clears, mandelic acid smooths and evens tone, and Biome-Sensing Tech + glutamic acid empower your microbiome to generate what it needs to thrive for balanced, healthier-looking skin. 

 

  • Biome-Sensing Tech + glutamic acid encourages a healthier, more balanced microbiome that's naturally more resistant to future breakouts
  • Glutamic acid "feeds" the skin's microbiome so it produces GABA, a protective amino acid for healthier-looking, smoother skin 
  • Salicylic acid clears and prevents acne, and penetrates deep to decongest clogged pores, while mandelic acid smooths and evens the complexion
  • Non-comedogenic, non-drying, non-irritating, layers well under makeup, no pilling or flaking, gentle enough for daily use

     

 

SKU: 15036
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Clearer skin starts in just 3 days*

Details

Getting skin clear is all about breakouts. Keeping it clear is all about a balanced microbiome. Get the best of both worlds with Murad's latest innovation that works as hard to clear breakouts as it does to keep your skin microbiome balanced. We merged trusted breakout-clearing ingredients like salicylic acid with breakthrough Biome-Sensing Tech that encourage a healthier, more balanced microbiome that's naturally more resistant to future breakouts—and that means smoother, clearer skin for the long run

*Consumer testing on 26 subjects in an 8-week study

Which skin type is it good for?
  • Balanced·
  • Oily·
  • Combination
Results

Unretouched real results

  • Clinically proven to deliver clearer, healthier-looking skin*
  • Clinically proven to reduce active breakouts*
  • Clearer skin starts in 3 days†


92% agree: no unwanted side effects†:

  • peeling 
  • flaking 
  • redness 
  • irritation


*Expert grading of photos on 26 subjects in an 8-week study 
†Consumer testing on 26 subjects in an 8-week study

INGREDIENTS

Expert, science-backed ingredients and patented technologies

CLINICAL NOTE

Why stop at clear skin? Our new Acne Serum not only treats and prevents breakouts, but also “feeds” good bacteria that empowers your microbiome to thrive—for balanced, healthier-looking skin

How-To
  • Step 1

    Massage Clarifying Cleanser or Clarifying Cream Cleanser over dampened face and neck. Rinse and pat dry

  • Step 2

    Apply 1-2 pumps of Biome-Balancing Clear & Prevent Acne Treatment Serum to face and neck; let dry completely before applying moisturizer, SPF, and/or makeup



  • Step 3

    Layering actives? Cycle your treatments! Use Biome-Balancing Clear & Prevent Acne Treatment Serum in the morning, and Deep Relief Acne Treatment at night

Get the Facts

  • Big zit, now what?

    How to shrink that breakout-fast Learn More

  • Skin freaking out?

    Why hormonal imbalance might be to blame Learn More

Overall rating: 4.888889 / 5 from 36 reviews.

AI Generated Review Summary

This acne treatment serum effectively reduces breakouts and redness, leaving skin feeling calmer, clearer, and healthier. It utilizes salicylic and mandelic acids to clear and smooth the complexion, while Biome-Sensing Tech and glutamic acid support a balanced microbiome for long-term skin health.

Summary topics

  • Skin Feel (40%): Many customers brought up that the product feels nice on the skin and leaves it feeling healthier.
  • Skin Clarity (44%): A substantial number of customers appreciated that their skin felt calmer, clearer, and less prone to flare-ups.
  • Breakout Reduction (18%): Opinions vary, but the Acne Biome Serum from Murad significantly reduces breakouts and redness.

Review topics: ["feels","skin","looks","works","breakouts","acne","pores","use","redness","reduction","difference","serum","treatment","change"].

Review highlights

  • "I really love that my skin not only looked healthier but felt healthier." — Amaris H.
  • "With consistent use, skin feels calmer, clearer, and less prone to flare-ups." — Gabriele M.
  • "Since starting the serum, the biggest change I have noticed is that my breakouts have become more manageable." — Kathryn

Reviews

Reduced inflammation and acne size!

"Absolutely love this product! It was great addition to my routine once I realized I had a damaged skin barrier. Chin acne improved significantly after a few days of use!"

— Whitney (5/5)

Light, smooth and calming

"It goes on smoothly, lightly - and you won't even notice it's on. I've seen a noticeable decline in blackheads, but it's taken a few months for me to get that result. Will continue to use."

— Raf (4/5)

It works!

"This product keeps my acne under control."

— Luz F. (5/5)

best product i’ve ever used

"i swear i refer to this as my magic serum. i suffer from horrible cystic acne and folliculitis and bizarre pimple-like bumps on my chest, back, neck, scalp, and bottom. I’ve tried almost every product on the market that is advertised to solve this kind of skin problem. The only product that ever has worked for me is this one - it’s incredible. If i skip one day of use, i’ll immediately see the bumps reappearing. I go through one bottle in two weeks. I need a larger size option!!"

— Danielle (5/5)

Biome-Balancing Clear & Prevent Acne Treatment Serum

"It helps me to not have any breakouts."

— Arlene R. (5/5)

Biome balancing gel

"I love this product. I alternate it with the deep relief acne treatment in step 2 of my face wash routine. The acne products work great to maintain clear skin and are the baseline facial treatment that I use regularly."

— Maura B. (5/5)

"Outstanding product! Helping to balance my skin."

— Christina (5/5)

like it!

"Obvious reduction of the redness and breakouts"

— Brooke G. (5/5)

the best for acne

"I stopped using the contraceptive and pimples appeared on my cheek. No product was helping me, until I tested this one. It was exactly what I needed: it improved acne without sensitizing my skin too much"

— Maria M. (5/5)

El mejor tratamiento para el acne

"Este tratamiento le ayudo mucho ami hija ella tenía brotes en toda la cara grandes y rojos y le ayudo a disminuir rotundamente la rojes gracias"

— Norma A. (5/5)

Q&A

How soon can I use the clarifying water gel after applying this serum?
Once applied, allow the serum about 60 seconds to absorb. Then apply the Clarifying Water Gel.
What percent of mandelic acid is in this?
The percentages used in our high-performance formulations are considered proprietary information and are not disclosed as part of our corporate policy.
Seeing different answers. Is this the replacement for the former “ Acne Clarifying Treatment “ that’s no longer available? Answers below state both “yes” and “no”
The Biome-Balancing Serum replaces the discontinued Acne Control Treatment. Its new formula adds mandelic acid and glutamic acid to clear acne and balance the microbiome.
My husband has acne scars on his face from when he was younger. I love Murad products and would love to get him the InvisiScar Resurfacing Treatment and see if this will improve his skin. I am just wondering when would be the most beneficial time for him to use since he shaves in the morning? Should he apply right after he shaves or before he goes to bed, etc?
He should use it both morning and night. Apply after shaving to instantly blur scars, then follow with SPF to prevent the scars from darkening.
Can I use this after my toners and it still be effective or does it need to come first?
You would use it after the toner and then follow with a moisturizer.

Frequently Asked Questions

1.0% salicylic acid, mandelic acid, glutamic acid, and Biome-Sensing Tech.

Acne-prone skin and those with mild-to-moderate breakouts, plus anyone wanting to improve uneven texture or tone.

Apply to clean skin morning and/or night. Use all-over or as a spot treatment. Allow to dry, then layer moisturizer and makeup as desired.

It's formulated to be non-drying and non-irritating and many users find it gentle, but individual reactions can vary.

Gel-serum: lightweight, slightly tacky on application, absorbs quickly. Minimal to no scent; some users note a faint floral note.

Yes. The formula layers well under makeup for most users and is reported to avoid pilling.

The formula contains salicylic acid at 1.0%.

Clinical testing was performed on those with mild-moderate acne. For deep, painful bumps and blemishes, we recommend Deep Relief Acne Treatment.

This serum clears all types of breakouts, from whiteheads to hormonal acne. And it prevents relapses using salicylic acid, mandelic acid, Biome-Sensing Tech, and glutamic acid to balance the skin's microbiome for healthier-looking skin.

Apply 1-2 pumps of the serum to clean face and neck. Let it dry completely before applying moisturizer, SPF, or makeup.

Yes, but do not layer. Rather, use Biome-Balancing Acne Treatment Serum in the morning and Deep Relief Acne Treatment at night.

The serum works for balanced, oily, and combination skin types.

It's clinically proven to deliver clearer, healthier-looking skin and reduce active breakouts, with clearer skin starting in just 3 days based on consumer testing.

Yes, it's non-irritating, non-drying, and gentle enough for daily use, with clinical results showing no redness, peeling, flaking, or irritation in testing.

Unlike typical treatments, it not only clears breakouts with proven actives but also uses Biome-Sensing Tech and glutamic acid to empower the microbiome against future breakouts for long-term smoother, clearer skin.

Yes, it's gentle enough for daily use, non-comedogenic, non-drying, and layers well under makeup without pilling or flaking.

Yes, this serum is designed to clear all types of breakouts, including hormonal acne.

It's formulated without parabens, sulfates, phthalates, gluten, and animal-derived ingredients.

Murad carefully assesses our products and ingredients to ensure they are safe for use. Because every person and pregnancy is unique, we recommend you seek your doctor's advice if you are unsure or have any questions about the products you use during pregnancy and/or lactation.