Straight From the Doctor

As the famed Nobel Laureat, Albert Szent-Gyorgi Von Nagyrapolt said, “Discovery is seeing, what everyone else has seen and thinking what no one else has thought.”

Scientific breakthroughs are rarely sudden and skincare discoveries are no exception. After working my way through medical school as a pharmacist, I found that research and compounding formulas were something I was very passionate about. Upon opening my medical practice in 1972, I started working closely with a cosmetic chemist, creating topical skincare blends to answer my patient’s individual needs. By the mid-80’s, when Glycolic Acid was a foreign substance to most, I had already tested various AHA’s on over 10,000 people, in search of ways to improve their acne, hyperpigmentation and wrinkles. Introducing the concept of AHA’s was not always easy, and I often heard, “What, you’re going to put acid on my face?”  A few years later, AHA’s became the industry standard for chemical exfoliation in the esthetic community. The introduction of these cosmeceuticals helped to propel the professional skincare market to the successful field it is today.

Beyond Cosmeceuticals
These topical solutions have prevailed, however the ideal client care goes beyond just topical care. We must not treat the skin in isolation. It is our body’s largest organ and responds best with an “Inclusive” approach to maximize its full potential. Providing inclusive care means addressing skin from the inside out, with foods and Internal Skincare® nutrients. An Inclusive approach also involves emotional health and lifestyle changes that reduce stress and isolation. And the underlying goal to every Inclusive Health® program is to boost cellular water; I call this the Cellular Water Principle™. Its basic precept is simple: when our cells and connective tissue are not fully hydrated, they cannot function at their optimal level. This leads to tissue damage we refer to as aging, and to dehydration that results in cell deterioration. When cells and connective tissue are filled with water, they are strong and can prevent the onslaught of disease and aging.

Addressing the “whole’ body is where the future lies in our industry. During the last few years of studying the skin, I have observed that even under great assault, from microbes, chemicals, and other environmental agents, the skin is resilient; it bounds back and wards off infection. This means there is a sophisticated defense system at work, maintaining balance and protection. Through this research, I’ve discovered the important connection between immunity and the skin.

When people hear the word immunity, their initial thoughts often gravitate towards vaccines, white blood cells, and infectious diseases. However, the body’s first and most influential line of immunity defense is the skin. By improving the integrity of the skin’s immunity, the body can be better protected by diseases, while also reducing the visible signs of aging.

The Skin and Other Body Systems
The human body is a complex organization. Every system of the body is connected to each other and must support each other to sustain life. These systems include:
Circulatory — consists of the heart, arteries and veins, for blood flow.
Digestive — includes the stomach and intestines to process food into minerals, amino acids and glucoses and passes them to the circulator system for delivery.
Endocrine — includes the pancreas and pituitary glands which release hormones to control metabolism, growth and development, tissue function and mood.
Urinary — includes the kidneys and bladder to filter out waste products from the blood and flush waste products from the body.
Lymphatic— includes the spleen and thymus to help remove foreign matter from body fluids.
Muscular — includes all muscle tissue and cardiac connective tissue which provide control and movement in other organs.
Nervous — includes the brain and spinal cord to receive and direct information to other organs.
Reproductive — includes ovaries and testes for reproduction purposes.
Respiratory — includes the lungs and trachea to take in oxygen and transfer it into the blood stream.
Skeletal — includes the bones and joints to protect vital organs and support all organ systems.
Integumentary — includes the skin, hair and nails to protect all other organs from attack by germs and viruses. Helps the body to minimize water loss.
Immune — includes highly specialized cells that work together to clear infection from the body.

The Integumentary System and The Immune System
Integumentary originates from the Latin word, Integumentum, meaning to cover or enclose. Comprised of skin, hair, nails, and associated glands; the Integumentary System enwraps the body, protecting it from harmful substances entering, while also keeping the necessary nutrients and moisture in.

The Immune System is made up of special cells, proteins, tissues, and organs, which work in synergy to respond to dangerous organisms such as viruses, bacteria and pathogens.

Skin Immunity – Innate and Adaptive
As the largest organ of the body, the skin also represents the largest organ of the immune system. When our immunity is working at optimum levels, the body has a biological defense that wards off infection, diseases and other unwanted invasions. When assaulted, the skin is flooded with a complex of peptides including Cytokines and Growth Factors. Functioning as messenger molecules, Cytokines and Growth Factors stimulate cellular proliferation, to repair and restore normal skin function.

There are two types of immune responses generated within the skin, these are innate and adaptive.

Innate Immunity and Keratinocytes:
Innate Immunity, also known as natural immunity is a type of protection that humans are born with. Considered the first line of defense, innate immunity also consists of certain cells; these non-specifically react on a certain aggressor. Innate immunity includes the external barriers of the body such as the skin, and mucous membranes, like those of the nose, throat and gastrointestinal tract.

1 The innate immune response represents a primitive, but quite effective reaction, which acts in a rapid but nonspecific way. It recognizes the aggressor it may not recognize it. Thus, in contrast to the adaptive response, it is characterized by the lack of immunological memory. Essential components of the innate response in the skin are cytokines, complement, and recently discovered, antimicrobial peptides. These are not in the skin normally, but when the attack happens, they can be produced by Keratinocytes.

Keratinocytes are structurally distinct with varying combinations of proteins. They perform numerous immunologic tasks, many of which are still being discovered. The keratin layer creates an effective barrier to prevent foreign matter from entering while maintaining structural lipids in the skin, minimizing moisturizer loss.

The Keratinocyte is representative of innate immunity. 2 In the last decade it has been discovered that Keratinocytes express Toll-like receptors, (TLR), potent sources of Cytokines, Chemokines and Antimicrobial Peptides. It has become clear that Keratinocytes may be more than active participants in epidermal immune responses; they may actually play a key initiating role.

Keratinocytes present the antigen and they produce their own cytokines, which are involved in encouraging immune response. They may also be involved in encouraging epidermal growth factors and fibroblast growth factors.

1 Skin Immunity, British Journal of Dermatology 2003/149 2 Innate Immunity in the Skin: How Keratinocytes Fight Against Pathogens/Current Immunology Reviews, 2005, 1, 29-42

Adaptive Immunity and Langerhans Cells:
Adaptive Immunity is a second line of protection that builds throughout our lives. Also known as active immunity, it involves the lymphocytes, and develops as we are exposed to diseases or immunized against diseases through vaccination. 3 The adaptive immune response is characterized by its specificity, and by the fact that it becomes more effective with each successive encounter with the same antigen (this means it has memory). Crucial components of an adaptive immune response are antigen (aggressor) presenting cells. In the epidermis, Langerhans Cells are the relevant aggressor cell.

Langerhans Cells abundant in the epidermis. They are Dendritic Cells (DC) with octopus-like arms that break up the invading micro-organisms and antigens (agressors). Their main function is to recognize antigen material and present it on the surface to other cells of the immunity system. Langerhans Cells are responsible for presenting antigens to T-Cells, which secrete Cytokines. 3 Skin Immunity, British Journal of Dermatology 2003/149

Histological Changes in Aging Skin
As we age our epidermal immune response diminishes. Langerhans Cells are diminished; Keratinocytes lose their ability to release Cytokines, cellular proliferation declines and the dermal layer atrophies, causing a loss in resiliency.

The skin is a major force of the body’s immune system. Arming immuno-compromised skin requires a 3-pronged, inclusive approach to renew and protect the skin topically, nourish the skin internally, and reduce the effects of stress through lifestyle modifications.

Fortunately, the skin’s immunity can be bolstered and through scientific research, I have discovered a new peptide that is independently proven to encourage an immune response.

The Research Behind the Immune Boosting Peptide
In a recent investigative study, working with scientists at the Scientific Center of State Research in St. Petersburg, Russia, I set out to first evaluate the immune-stimulating properties of a newly discovered peptide. This isolated peptide of algae origin was demonstrated to effectively up-regulate the activity of growth factors in healthy tissues and cell cultures. The gene of this peptide was cloned, the producer strain was created, the technology of extraction and purification and control methods were developed, and clinical tests were carried out. The preparation is called Nonapeptide-78 and it is exclusively used in some of my most recent esthetic formulations.

The Nonapeptide—78 has been tested clinically in three different methods:
Test Method 1: Cell Culture on Keratinocytes
In invitro cell cultures the Nonapeptide-78 was shown to cause the increase in Keratinocyte and epidermal growth factors.

Test Method 2: Culture of Mononuclears of Peripheral Human blood
In a second invitro test, the Nonapeptide-78 was shown to increase the expression of the genes of fibroblast, epidermal and endothelium growth factors in mononuclears extracted from the peripheral human blood. Correspondingly, fibroblast, epidermal and endothelium growth factors increased. Interleukins 6 and 8 were increased in cultures with the Nonapeptide-78 versus the control showing no increase in IL6 or IL 8 in the absence of Nonapeptide–78.

Test Method 3: Skin Biopsies in trauma patients
In skin biopsies taken after 4-6 hours after the application of Nonapeptide-78 the gene expression of Keratinocyte, epidermal growth factor and the basic form of fibroblast growth factors were increased versus the untreated skin in the same panelist.

Preliminary research shows Nonapeptide–78 stimulates the proliferation of genes and growth factor genes. Nonapeptide–78 sequences the growth factors in cultures to stimulate the proper stem cells to fission and to differentiate into skin cells, fibroblasts and Keratinocytes. Fibroblasts are responsible for synthesis of elastin, glycosaminoglycans, and the synthesis of collagen. 

Young skin readily regenerates collagen, elastin and glycosaminoglycans. In aging skin, the quantity of active fibroblasts is greatly reduced which means that synthesis of collagen and elastin decreases. By utilizing the benefits of this new peptide technology, we can stimulate cells to increase the rate of skin cell regeneration and restores skin’s ability to regenerate faster.

Recap
Aging can be characterized by a decline in an individual’s ability to respond and defend itself against stress, environmental damage or internal disorders. It is well documented that the immune function of humans and other animals declines dramatically during the aging process, increasing the incidence of immune associated diseases.

Advances in biotechnology have presented the therapeutic properties of sequenced peptides that show immense promise in enhancing cutaneous immunity, while increasing specific growth factors responsible for Keratinocyte and Fibroblast activity. 

When these advancements are utilized in topical applications, nutritional elements and lifestyle programs, the skincare professional is truly practicing the next generation of skin health.

To learn more about skin immunity, these reference articles provide a depth of knowledge. In addition, you can inquire about advanced skin immunity seminars through our senior medical education team at 1-800-33-MURAD. Additional Reading Materials:

The Nuero-Immuno-Cutaneous-Endocrine Network (N.I.C.E.): Relationship of Mind and Skin, Archives of Dermatology / Volume 134, Nov. 1998.

Innate Immunity in the Skin:  How Keratinocytes Fight Against Pathogens, Current Immunology Reviews, 2005 / 1

Skin Immunity, British Journal of Dermatology 2003 /  149

Who is really under control with skin immunity under physiological circumstances, Experimental Dermatology, 2006 / 1

Every year, American men are spending more on skincare products. According to Euromonitor, the men’s segment is one of the primary drivers of growth in the U.S. skincare market, having grown 42% between 2000 and 2005, compared to 23% for the market as a whole.

Men and skincare are two things that traditionally have not gone together -until recently. In today’s culture, there is a newfound acceptance among men of taking an interest in their looks and paying extra attention to grooming. Men are no longer considered effeminate when they request skincare products by name. The stigma of using skincare products has faded, and the man who cares about his looks is finally in style. Today’s increasingly appearance and health conscious man is starting to notice that he is not immune to common skin concerns, and he wants to do something about them.

As men have become more aware of their skin, more are able to identify what skin-type they have, be it oily, dry, sensitive or combination. Men are also starting to pay more attention to the quality of products and be brave about their purchasing decisions - using more than just soap and water or drugstore shaving cream. Today’s man is venturing into new product categories such as cleansers, scrubs, toners, wrinkle creams and eye treatments in numbers unprecedented by his no-fuss counterpart of the past.

In order to meet this new demand, brands and service providers must keep two factors in mind. The first is the unique physiology and skin conditions that men face. The second is that the way men view products and treatments is different from the way women do. This is something we in the industry need to be sensitive about.

Men's Skin Physiology and Concerns
Men’s unique set of skin care needs often necessitates their own product category. Borrowing their wife or girlfriend’s moisturizer might work once in awhile, but not everyday. Men’s skin is typically thicker and more oily then women’s, and their products should reflect this. Also, men generally prefer less fragrance in their products then traditional “female” products have.
Shaving is often the factor that causes the biggest discrepancy in the skincare needs of men and women. Along with general irritation and razor burn that results from dragging a razor across one’s face every day, many men also suffer from pseudofolliculitis, a condition in which hair grows back into the skin, irritating the hair follicles and causing itchiness, inflammation, and bumps. For these reasons, men need products that exfoliate the skin to uncover ingrown hairs, while simultaneously delivering soothing and hydrating ingredients to address redness, irritation and dryness. The market is now beginning to address these concerns with high-quality products that call out these benefits in a way that is more compelling to men.

Men's Views on Skincare The industry is now creating products and treatments that not only address men’s unique skin concerns, but that are also more receptive to their perceptions of skincare. Men are becoming more aware of wrinkles, acne and discoloration and are realizing that they too can benefit from products that in the past have mostly been used by women. However, they also tend focus on products that address specific problems that they are currently having, rather than choosing products that are preventative. In a market research study we recently conducted, most respondents said that acne, razor-burn, and dryness are their only skin concern. Due to this tendency towards a narrow focus on their needs, men often avoid caring for their skin until the damage has already been done in the form of acne scarring, wrinkles or discoloration. Already damaged skin increases the need for targeted treatment products. It is our job as industry innovators to educate our male clients about treatment options that can address future as well as current needs.

Men are surprisingly unaware of the importance of sun protection, and typically don’t incorporate sunscreens with SPF into their daily regimen. This should be the easiest and most self-evident step in grooming and overall health prevention for both genders. There are several opportunities to introduce men to SPF products - to both educate them on the importance of protection, as well as on how to combat environmental damage. Many new products targeted to men contain an SPF to help streamline the grooming process.

Nobody wants to add more tasks to an already busy schedule. Men are certainly no exception, and prefer easy 1-2-3 step systems of products to make the grooming task fast, easy and efficient. They are particularly interested in products that do two things at once – such as combining an acne and an anti-aging formula into one. Regimens containing more than 4 steps are intimidating to many men and can hinder them from trying a new system. With men, simplicity is best.

In this vein, we are now seeing an influx of simplified, multi-functional products with names and packaging that speak to men specifically. Studies show that men gravitate towards products that easily identify their purpose and specify the benefits provided. Product benefit call-outs have a stronger effect on men then do specific ingredients. As long as the products are perceived to work, men are not concerned with why or how they work. Research also suggests that men are more drawn towards products that call out to them, with words such as “MEN” or “MAN” appearing somewhere in the packaging.

Due to its relative youth, men’s skincare is a constantly evolving market. As men become more and more interested in grooming and skincare products, professional salon facial services are following close behind. At the Murad Medical Spa and Murad Inclusive Health® Center, we find that male clients are committed to following their esthetician’s recommendation, and they are very open to booking a series of services. The key to success is scheduling their services when they are there and making the confirmation calls. Once they write it in their calendar, the male client is a loyal one.

Classifications of the Male Consumer
While gay men have traditionally been the pioneers in the areas of style and grooming, straight men are beginning to follow their lead. Building a loyal male clientele starts with matching various age groups and classifications of men to the benefits and needs that most closely match their type.

The 3 Types of Straight Men
Metrosexual– The metrosexual is an upwardly mobile heterosexual male who is very interested in his appearance and grooming, and is always willing to try a new product or spa service.

Ubersexual– Ubersexual is a new classification among today’s men. He is interested in his appearance and grooming, but tends to be more traditionally manly and rugged then the metrosexual man. The ubersexual man is open to products and services, but often requires that they be presented in a masculine way, with more manly names and packaging.

Traditional– Depending on his age, the traditional heterosexual man is generally considered a non- skincare user, with the exception of soap, deodorant, and shaving products. Once introduced to 1-2 products, usually through a female, however, he can become quite a loyal user, as he begins to notice the quality of his skin improve. The traditional man is often more interested in health then beauty. For example, he will respond more to a product that will help “prevent skin cancer,” then one that will “prevent spots.”

Age targets will further help to focus the best product or service to the man.

The 3 Age Groups of Men
15 – 25: Acne on face, chest and back are the most common concern for this age group. Keep their regimens simple – one to two products starting with a cleanser and treatment. Deep cleansing facials and back facials should be kept at a 30 minute timeframe.

25 – 40: This age group is most interested in grooming and relaxation. They look for ways to get a close, shave and leave their skin soft and smooth. They are more open to eye treatments and sun protection products then their younger counterparts, as well as longer, more relaxing spa treatments.

40 & up: To stay competitive in the work place, they look for ways to improve their looks and reduce signs of aging. They are open to products and services that are problem/solution focused. Sun damage, broken capillaries, wrinkles and eye puffiness are common concerns. This age category is an ideal target for internal skincare® supplements.

The “Average Joe” is starting to change his ways, and use above-average skincare products and regimens. It’s a new day for men’s products, as the market will only continue to grow. Clear, healthy skin doesn't have to take a lot of effort, and using the right skin regimen will separate the men from the boys.

An essential part of eye care is eating the right roods that contain the proper vitamins to maintain eye health. There are many eye problems and diseases that can be avoided through the intake of nutritious foods. My favorite saying is “before there was medicine, there was food.” With this in mind, I’ve outlined the most common eye concerns and the top foods and nutrients I recommend for healthy eyes.

Dry Eyes Dry eyes are a very common syndrome with varying degrees of severity. This condition affects more women than men with research showing 6 million women and 3 million men in the United States having severe cases, up to 30 million people having mild cases.

While it is important to see your doctor if you are experiencing severe dryness, there foods you can incorporate into your diet to ensure you are lubricating the eye internally. A diet high in Essential Fatty Acids and Lecithin will keep and attract water in the cells, providing hydration. Add Olive Oil, Flaxseed Oil, Borage Seed Oil to your diet. Eat cold water fish, eggs, soybeans, tomatoes and peanuts to benefit from the lecithin they contain.

Broken Blood Vessels
Small red veins within the eye are common, yet they can sometimes they can appear overnight. They can occur from coughing, sneezing, eye strain, or rubbing the eye. They are more common in people that take blood thinners or aspirin regularly.

Since the skin around the eye is one of the thinnest on the body, broken blood vessels can show through, causing the look of a dark circle.

Foods high in Vitamin C and Bioflavonoids such as berries, oranges, grapefruit, and apricots help to reduce broken blood vessels and promote new blood vessel growth. In addition to colorful fruits and vegetables, one of my favorite foods is the Goji Berry. Grown in the Himalayas, Goji Berries are considered to be one the of the worlds most nutritious foods. Ounce per ounce, Goji Berries contains more Vitamin C than an orange and over 21 trace minerals and amino acids. They are available in dried form and are also found within nutritional dietary supplements.

Glucosamine is another vessel support nutrient. This amino acid strengthens collagen and elastin tissue, which is what the blood vessel is comprised of. It is not commonly found in foods; therefore taking dietary supplements are recommended.

Dark Circles
Due to the thin and delicate anatomy of the skin around the eye area, dark circles and even dark eyelids are very common. The darkness is often due to the blood vessels that are found beneath the skin’s surface.
Dark circles, like varicose veins are usually an inherited trait. In darker skinned people, exposure to sunlight can cause a melanin surge, causing the skin to become even darker. Allergies, asthma and the common cold may also contribute to dark circles under the eyes, as people are more likely to rub the area.

Fatigue plays a role in dark circles. A lack of sleep or excessive tiredness can cause paleness of the skin, which again allows the blood underneath to become more visible and appear darker.

Age can also take its toll on the under eye area. As the skin becomes thinner with age, dark circles and appear more prominent. Excess folds of skin under the eyes will also make dark circles more pronounced.

In addition to getting proper rest, key nutrients are necessary to maintain blood vessel strength. Attracting water to the skin and encouraging healthy collagen and elastin formation can be done through ingestion of foods rich in Vitamin C and Bioflavonoids. (see foods listed under broken blood vessels above)

Puffiness
Swollen, puffy eye lids and under eye puffiness are a result of extracellular water, also known as wasted water, which leaked from our cells, and has accumulated in the area. Whether it’s swollen ankles or swollen eyelids, my theory called The Cellular Water Principle™; is the answer to turning this wasted, unused water, back into the valuable water that should reside inside our cells, not outside our cells.

Over time, our cells and other areas of our bodies that need hydration break down and become unable to hold onto the water, leaving them weakened and less effective. When our cells are not fully hydrated they can not function at their optimal level, and side effects, such as puffiness can occur.

By adding key, cell-strengthening nutrients to your diet, you can reduce the puffiness caused from wasted water accumulation. Eat foods rich in the polyphenols, these are super antioxidants. One of my favorites is pomegranate extract. Pomegranate extract can be taken as juice, fruit or seeds, or as a standardized extract in supplement form. The supplement form is ideal as it is easily accessible year round.

Foods rich in Lecithin a key cell strengthener are important. In addition to eggs, eat a variey of soy products including tofu, edemame, and soy milk. Lecithin granules can be added to smoothies s ors sprinkled on cereal. Tomatoes, spinach, cauliflower and peanut butter are additional sources. Essential Fatty Acids absorb water into the cell and will also help to reduce puffiness. Eat Olive Oil instead of butter and add raw, unsalted walnuts, almonds and cashews to your diet.

Introduction
Each and every day, the skin – our body’s largest organ – is bombarded with environmental assailants. In addition to external aggressors such as pollution, smoke, and ultraviolet radiation from the sun, the body’s own metabolism causes cells to sustain one thousand hits of free radicals daily, triggering the release of inflammatory mediators which break down collagen and damage cell barriers. In fact, internal damage caused by free radicals not only leads to the esthetic concern of wrinkled skin and hyper pigmentation, studies have shown this to be one of the main factors contributing to the formation of cancerous cells.

Since my early days as a dermatologist, I have been studying the ability of various antioxidants, such Vitamin C, Coenzyme Q 10, Alpha Lipoic Acid, and Vitamin E and herb extracts such as Burdock Root, Echinacea, Yellow Dock Root, and Grape Seed Extract to repair and protect the skin against such damage. While all are extremely beneficial, I found the most potent antioxidant power to date comes from Pomegranate Extract, and specifically the polyphenol, Ellagic Acid contained within the pomegranate.

In this paper, I would like to demonstrate pomegranate’s ability to boost not only skin’s external defenses against harmful free radicals and environmental stressors, but also demonstrate that a standardized extract of pomegranate extract derived from the whole pomegranate fruit, has potent polyphenols that stimulate an increase in the body’s own built-in antioxidant, glutathione, and increases the topical SPF of sunscreens.

Historical Implications of Pomegranate
A native plant of Northern Africa, pomegranate (Punica granatum L) is one of the oldest natural remedies known to man. P granatum was mentioned in the papyrus Ebers of Egypt written in about 1550 BC. Hippocrates described its medicinal powers. Doctors in Greece prescribed pomegranate juice as a remedy with multiple activities: anti-inflammatory; as a potent anthelmintic (acting to expel or destroy intestinal worms), chronic diarrhea, dysentery, and cough suppressant.

In Mediterranean and Caucasian folk medicine, pomegranate extract is used to strengthen the human capillary system, for anti-atherosclerosis, as an anti-asthma agent, and for tonsillitis and bronchitis. Several scientific groups have reported anti-bacterial activity of polyphenols extracted from pomegranate and when mixed with aloe extract, pomegranate extract has been shown to activate bone tissue regeneration after injury.

Pomegranate extract is rich in a different group of polyphenolics, including anthocyanidins such as pentoside of malvidine and petunidin, delphinidin 3-glucoside and cyandin 3, 5 diglucoside. The analysis of biochemical composition performed at several Russion and Spanish Universities indicates that polyphenols (35-40%) and Ellagic Acid (5% -10%), are the main constituents of pomegranate extract.

Ellagic acid is a naturally occurring phenolic constituent of many plants that are important in the human diet, especially fruits and nuts. Interest in Ellagic acid has increased greatly during the last decade due to its effectiveness as an antimutagen and anticarcinogen and its potential as an inhibitor of chemically-induced cancer.

Efficiency of Pomegranate Extract, Topically and Internally
Topically, pomegranate extract is especially effective in protecting cells from free radical damage by inhibiting the formation harmful enzymes that cause cells to grow out of control. The ellagic acid, found within pomegranate extract is also thought to strengthen the cell membrane, making it less susceptible to free radical damage and preventing water loss. Such properties have important implications in terms of cancer prevention, as out-of-control cell division is a hallmark of cancer.

Indeed, research continues to support the anti-cancer and healing benefits of topically applied Pomegranate Extract. In a South Dakota State University study entitled Chemopreventative Effects of Pomegranate Seed Oil on Skin Tumor Development, Pomegranate Extract was applied to topical skin tumors on mice. After five weeks, the study concluded that topical application of pomegranate oil inhibited papilloma incidence and activity.

Researchers at the University of Wisconsin, evaluated pomegranate's anti-skin tumor effects by comparing topical application of pomegranate extract on neonatal mice against TPA-induced markers (12-0-tetradecanoylphorbol-13-acetate), a strong promoter of chemically induced skin cancer. Applying pomegranate extract onto the skin of neonatal mice 30 minutes prior to TPA application significantly inhibited TPA-mediated increases in skin edema and hyperplasia, they said.

They also tested the pomegranate extract on TPA-induced skin tumor promotion. The animals pretreated with pomegranate extract showed substantially reduced tumor incidence and lower tumor body burden. In the TPA treated group, all mice developed tumors at 16 weeks, whereas only 30 per cent of the mice treated with pomegranate extract exhibited tumors at that point.

The protective and healing properties of the pomegranate are extremely important today, as the rate of skin cancer is increasing faster than any other cancer among Western countries. Applying sunscreen alone isn’t enough. The challenge is to teach our clients to apply enough and re-apply to cover all areas of the skin from head to toe.

Internal Benefits of Pomegranate Extract
Using independent, scientific research methods, I have tested the pomegranate’s ability to improve the sun protection of sunscreen and found a 20 percent boost in SPF when pomegranate is added to a topical formulation. I then set out to test the result of oral ingestion of pomegranate extract.

Perhaps the most extraordinary result of this research is the discovery of pomegranate’s age-proofing capabilities and healing benefits. When taken orally, this radically innovative ingredient boosts the SPF rating of topical sunscreens so that the same SPF protection levels are maintained, using fewer chemicals and more antioxidants.

Pomegranate Extract Study Overview
The following is an overview of a blinded controlled independent study performed by Clinical Research Laboratories, Fairfield NJ Blinded: The subject is not aware of the identity of the test material they are receiving (placebo or active, benchmark or test material). Double Blinded: Neither the subject nor the evaluator is aware of the identity of the test material each subject receives.
Controlled: The study has either an untreated control site/group or a placebo site/group.
?Monadic: Study in which each subject serves as his own control (e.g. post treatment data is compared to baseline data using paired statistical tests).

Objective
To evaluate the SPF value of four sunscreen formulations following daily ingestion of one of two antioxidants (pomegranate capsules and mixed fruit capsules) for a period of one week.

Test Materials
SPF-4 Lotion Homosalate
SPF-4 Lotion with antioxidants and Homosalate
SPF-8 Lotion with Octyl Methoxycinnamate
SPF-8 Lotion with antioxidants and Octyl Methoxycinnamate Pomegranate Capsules
Mixed Fruit Capsules

Inclusion Criteria
Male and Female panelists ranging in age from eighteen (18) to sixty (60) years old were selected for the study. Panelists with fair skin (levels I. – III.) were selected, determined with the following guidelines:
Always burns easily; never tans (sensitive)
Always burns easily; tans minimally (sensitive)
Burns moderately; tans gradually (normal)
All panelists signed an informed consent and completed a Panelist Profile/Medical History form provided by Clinical Research Lab prior to the study. Exclusion criteria included subjects with any abnormal reaction to sunlight, known allergies to any of the components in the test article, (fruits or fruit-derived vitamin supplements), subjects who use UVA sunbeds or anyone exhibiting any visible skin disease.

Test Method
Thirty-two subjects who met the inclusion criteria were selected for participation. Day 1— determination of Minimal Erythemal Dose (MED).
Using Xenon Arc Solar Simulator (150w), subjects were exposed to light with a continuous emission spectrum in the UV-B range (290-320 nanometers) during the testing. Prior to testing phase, the MED of the unprotected skin of each subject was determined by a progressive sequence of timed UV light exposures, graduated incrementally by twenty-five percent (25%) over that of the previous exposure.
Days 2-3 —
Sixteen to twenty-four hours after irradiation, the sites were evaluated for erythema.
Days 4-9 —
Subjects returned to the clinic to ingest their assigned antioxidant. All dosing of the capsules was supervised.
Days 10-11 —
Testing sites were outlined and irradiation procedure performed, to determine MED.

Results
Significantly increased SPF of test material SPF 4 Homosalate by 28.8%
Significantly increased SPF of test material SPF-8 Octinoxate by 22.7%

Conclusion
This is a pilot study demonstrating the potential of oral/internal sunscreen. Based on this research, adding pomegranate extract boosted the SPF of the sunscreen formula by 20 percent. Over and above that, ingesting a tablet of standardized pomegranate extract provides an additional 25 percent improvement in the SPF.

Summary
Topical application of sunscreens containing pomegranate extract is very effective at increasing sun projection. Also, the internal benefits of ingesting 15mg standardized extract of pomegranate extract containing 5% ellagic acid, is so impressive, I have integrated pomegranate extract as a part of the topical and internal skincare of my patients.

Indeed, the protective and healing properties of the pomegranate are increasingly important today, as the rate of skin cancer is increasing faster than any other cancer among Western countries. Further research regarding pomegranate extract is necessary to fully realize the healing and protective properties of this medicinal food.

Working in my dermatology practice, I’ve been asked many times, “Is it better for me to use an all natural product? My skin is so sensitive and I’m looking for one without chemicals, what do you suggest?” I do my best to educate my patients on the truth – there is no such cosmetic product made of 100% all natural, chemical-free ingredients. All products are made of chemicals.

The reaction of these chemicals working together happens all the time in nature, in laboratories to create new compounds and in the human body to assist cellular function, produce energy and ultimately sustain life.

Consumers are often confused and frustrated about what is healthy for their skin, and there has been a misconception about chemical-free, synthetic-free and 100% natural products. However, all products and materials on earth are made up of chemicals. Everything from the chair you’re sitting on, the paper that makes up this page and the ink used to print the words to the water you drink everyday is composed of chemicals. Life is chemistry and everything, natural or synthetic is composed of chemicals.

There is a lot of misunderstanding right now in the skincare and spa industry over which ingredients are healthy for skin. Regardless of origin, each ingredient can be safe while also having the potential for adverse effects.

Both naturally derived and synthetic products are tested to assure safety regardless of their origin.

What is natural?
“Natural” can be defined as arising from a state produced by nature without interference of humankind. Consumers often believe that using products with natural ingredients are better for their skin. However, in reality, it is often the synthetically derived ingredients that increase the efficacy of natural ingredients. Products containing “natural” ingredients often occur in a small extract of the source, which is usually not enough to deliver results on its own. Other times, some natural ingredients only require small amounts to be functional, depending on the formula.

A common myth about natural ingredients is that they are better for the skin, however they are just as beneficial for the skin as their synthetic counterparts. For example, a product with vitamin C will contain ascorbic acid, the technical name for vitamin C. The molecular structure of ascorbic acid is the same as its natural counterpart, regardless of it being naturally derived or produced synthetically in a laboratory. A formulator might choose to use synthetic vitamin C over the natural version because it is more readily available, more pure and potentially more functional.

“Naturally derived” refers to a substance with a natural origin that is chemically or physically modified to make it more functional. This category may include extracts from herbs and flowers by concentration, which would aid solubility or proteins broken down to create smaller peptide molecules. However, natural ingredients do not guarantee any kind of efficacy. As with all ingredients, their efficacy must be tested and validated.

Why synthetic?
“Synthetic” ingredients are human-made substances. Synthesis is the formation of a compound from elements or similar compounds. In fact, synthetic ingredients are often more functional than their natural counterpart. Since they are created in a lab, these ingredients will deliver consistent results and high quality every time, assuring control over the reliability of the ingredient.

Oftentimes, complex ingredient names with several letters and starting with prefixes like acetyl- and propyl- will make the user worry about what they are putting on her face. For many people the word synthetic gives rise to negative images. Natural, on the other hand makes people think of products that are “pure” or “free of chemicals.”

While it is true that many natural ingredients are used in cosmetic products, all natural products must undergo chemical processing to be purified, modified, concentrated and preserved to make them more functional and viable over time. For example, an orange extract cannot exist in skincare products without being treated first, but a chemically synthesized extract of an orange can. All cosmetics must contain a preservative system to protect the formula from oxidation or spoilage despite the manufacturers claims to the contrary.

And while some products may contain antioxidants such as vitamins C or E, these vitamins are often synthetically derived, as well. Studies that evaluate the functionality of ingredients, regardless of origin, show that natural ingredients are not necessarily better than their synthetic counterpart. For example, glycolic acid is produced synthetically to yield higher concentrations that are more available than found in nature. The same applied to salicylic acid – its synthesized version is purer, more bioavailable than its natural source from willow bark.

Many people also do not realize that synthetic and natural ingredients must co-exist to make the other effective. For example, a sunscreen may use Titanium Dioxide, which is natural, as its key over the counter therapeutic (OTC) sunscreen ingredient. The formula may also utilize sodium hyaluronate, which is synthetic, for hydration and silicone for spread ability on the skin. Additionally, using both types of ingredients are essential to create a working formula.

Walk into any health food store and you will see multiple skincare products claiming to be “all natural” and” free of chemicals”, but in reality, these products do in fact contain chemicals. Common “all natural” ingredients such as water, vitamins, pomegranate and plant extracts are actually chemicals because all matter is composed of chemicals. When it comes to organic, it is important to know that the U.S. Department of Agriculture does not regulate the use of the term “organic” or “natural” on products, therefore any formula can call itself “organic” or “natural” without penalty or proof. It’s likely that many products claiming to be “organic” or “natural” are using it as a marketing tool, and not based on scientific fact.

Where do you go from here?
Utilizing both forms of ingredients will yield the best overall results for optimal skin health. Below are few of my favorite synthetic and natural ingredients.

Top Synthetic Ingredients:
Alpha Hydroxy Acids (AHA’s) / Glycolic Acid, Lactic Acid: Alpha Hydroxy Acids, Glycolic Acid and Lactic Acid are often used in skin care products because of their ability to penetrate the skin, and to help stimulate collagen and elastin production. These ingredients can also be naturally occurring in sugar cane or milk. Salicylic Acid: This chemical compound causes skin cells to slough off quickly to help prevent pores from clogging. Because of its properties, it is often used in acne products. This ingredient is naturally occurring in willow bark.
Silicones: Silicones are often used as emollients, such as lubricants, and thickeners to help smooth the skin.
Retinol: A derivative of vitamin A, Retinol helps reduce hyper-pigmentation, fine lines and wrinkles, while improving skin texture and restoring hydration levels.
Synthesized Peptides: Formulated to work like naturally occurring peptides, the synthesized version stimulate collagen production and promotes elasticity.
Hydroquinone: This bleaching and lightening agent is a popular ingredient in skin care products and often used to treat hyperpigmentation.
Avobenzone: Most often found in sunscreen, Avobenzone absorbs UVA and UVB rays.
Glycerin: Glycerin is often used as an emollient, humectant, and solvent, in personal care products.
Sodium Hyaluronate: Also known as Hyaluronic Acid, this ingredient has moisturizing properties and helps retain water in skin cells.
Ceramides: Ceramides (synthesized sphingolipids) are used to smooth skin and interact with the top layer to protect water loss.

Top Natural Ingredients:
Water: Water is the most common ingredient in skin care products, and is included to hydrate skin and to help other ingredients penetrate the skin. While water is natural, it is not taken directly from the tap and mixed into a skincare formula, it first must be sterilized, a form of synthetic processing.

Titanium Dioxide: This mineral ingredient acts as an invisible light reflector and is used as a sunscreen.
Zinc Oxide: Zinc Oxide, another mineral reflects both UVA and UVB rays and is also used to to protect against sunburn and other damage to the skin caused by ultraviolet light.
Goji Berry Extract: A small berry loaded with antioxidants, trace minerals and amino acids, it is included in anti-aging, anti-redness and firming products.
Pomegranate Extract: This fruit extract is a powerful antioxidant and has been scientifically proven to be effective in boosting sun protection.
Polysaccharides (yeast extract): Polysaccharides help form a water-binding film on the skin to protect the skin from water loss and may assist in boosting immune function.
Petrolatum: A mineral oil jelly, this common ingredient is often found in skin lotions and cosmetics to improve skin barrier function and prevent transepidermal water loss.
Colloidal Oatmeal: This oat ingredient helps soothe, moisturize and relieve dry skin.
Sulfur: Used for problem and acne-prone skin, sulfur
Evening Primrose Oil: This essential fatty-acid hydrates the skin to helps restore the moisture and lipid balance to dry skin conditions. Regardless of the ingredient origin, natural or synthetic, what’s more important is the final product safety profile and proven effectiveness. People should understand that all ingredients, natural or synthetic are chemicals. Moreover, just because an ingredient might be harvested from the ground, and “natural,” it might not necessarily be good for the skin, and vice-versa – just because an ingredient is synthetically produced might not be harmful to skin.

Scientists and researchers have come a long way in their efforts to understand the properties and benefits of supplements in skin care. The use of vitamins and other nutrients to hydrate, normalize, protect, heal, condition and beautify the skin appears to be the wave of both the present and the future. Clearly, the internal use of vitamins is one of the most powerful weapons in the ongoing quest for younger, healthier, more attractive-looking skin.

I've been recommending dietary supplementation to my patients since I began my practice in 1972. While completing my Dermatology residency, I worked as a pharmacist and have always believed that nutritional supplements benefit the skin, and promote overall body health. I've devoted years of research in the fields of nutrition and skin health. Why?... you may ask, is a pharmacist and dermatologist recommending vitamins and supplements to his patients? Why devote so much energy and time to nutrition when the clients have acne, wrinkles and sun damage?

The answer is simple – the skin is an organ. It is the body's largest organ, and it is attached to every other cell and organ in the body. This is the foundation of any type of professional skincare treatment. The fact that the skin is connected to every other organ in the body should be at the forefront of understanding in every estheticians mind, and the basis for thorough consultations.

Let's take a closer look at the skin.
?When we treat the Epidermis with topical facial products, we address approximately 20 percent of the skin. The remaining 80 percent, the dermis, which contains the cells and connective tissue featuring collagen, elastin fibers, and blood vessels, needs to be addressed from the inside. The way to do this is through nutritious foods and added support through supplementation.

It makes perfect sense - eat well, get better skin, but feeding the skin all the nutrients it needs to keep cells and connective tissue –strong and well hydrated is not that easy. Research tells us that Americans are overfed, they are not necessarily well nourished. Even the 20 percent of Americans who make the effort to consistently eat the recommended minimum of five servings of fruits and vegetables a day may not be getting the vitamins and minerals they think their healthy eating guarantees. The amount of vitamins available in foods depends on where they are grown, how fresh they are, how they have been stored, and how they are cooked.

Did you know the “fresh” apple you buy at the grocery store has been picked, and stored, then shipped and stored, and after weeks, is finally on the grocery shelf? During the time it takes to get the apple to the store, it is losing its nutrient content. This means that even if we do consume fresh, preferably organic raw fruits and vegetables, we are still not gaining the full nutrient content as if we ate it right off of the tree.

According to a recent survey commissioned by the Council for Responsible Nutrition (CRN), 58 percent of Americans acknowledge they do not eat a balanced diet on a regular basis. The American College of Nutrition reported that 46% of a family's expenditure on food items went towards unhealthy fast food. In today's fast paced world it's a challenge to get all of the essential nutrients necessary to look good and feel good. So as an esthetician, what can you do?

My vision of an esthetician is that of a healthcare provider. Think about the impact you have on your client's health, what other professions provide the emotional care through healing touch? Or the topical care with skin smoothing and hydrating services? You can round out the emotional and topical care you provide by educating your clients on the nutrients necessary for your body's largest organ – the skin. This is the internal care.

Let's take a look at the key nutrients necessary for supporting healthy skin and promoting overall health:

Collagen and Elastin Support: Starting at age 20, our collagen starts to diminish by 1 percent each year. Feed the body what it needs to manufacture it's own collagen and elastin. The matrix of the dermis is comprised of chrondroitin, dermatan and hyaluronic acid. To make these substances, your can body convert them from a nutrient called glucosamine. Your body produces glucosamine but not in sufficient amounts to replenish all of its connective tissue. A dosage of 1,000 to 2,000 mg is suggested.

Amino Acids: When we eat protein-containing foods, our body breaks the protein down into various amino acids, then absorbs these amino acids and rebuilds them into the sequence that we need for specific body tasks. Out of 20 amino acids, only 11 can be manufactured by our body. The 9 amino acids that we cannot make are called essential amino acids. In addition to taking an essential amino acid complex, a diet rich in beans, whole grains, nuts, seeds, tofu and lean proteins such as fish or chicken.

Essential Fatty Acids: EFA's are necessary for attracting water and keeping water in the cells. The Cellular Water Principle® program that I recommend for my patients is based on protecting the cell walls, keeping water in. Essential Fatty Acids, such as Omega-3 oils are vital for a healthy heart and a healthy brain, plus they provide internal hydration which can make dramatic changes in eczema conditions or severe dryness. Since the body does not make its' own essential fatty acids, they must come from food sources or supplements. I recommend two, 1,000 mg of fish oil EFA supplements every day in addition to consuming plenty of cold-water fish, olive oil and flaxseeds.

Vitamins and Trade Minerals: To metabolize the glucosamine, amino acids and EFAs into new healthy connective tissue, the body needs B vitamins and trace minerals including maganese, magnesium, copper and zinc. I recommend a daily multivitamin/multi-mineral supplement that has at least 100 percent of the Daily Value (DV) for all 8 of the B complex vitamins.

Daily B Vitamin Requirements
Niacin ( B3)     20 mg
Pantothenic Acid (B5)     10 mg
Cobalamin (B12)      6 mcg
Pyridoxine (B6)      2 mg
Riboflavin (B2)      1.7 mg
Thiamine (B1)      1.5 mg
Folic Acid      400 mcg
Biotin      300 mcg

Daily Mineral Requirements
Magnesium     400 mg
Iron*      18 mg
Zinc      15 mg
Copper      2 mg
Manganese      2 mg
Iodine      150 mcg
Chromium     120 mcg
Molybdenum      75 mcg
Selenium     70 mcg
Calcium    1,000 mg -1,500 mg
Choose an iron-free multi-vitamin/ multi-mineral formula if you are post-menopausal.

Antioxidants: Vital to protecting the skin and the organs from free radical damage, these are a few of my favorites.
Pomegranate Extract     15 mg
Curcumin (Tumeric)     45 mg
Grape Seed Extract      100 mg
Quercetin     15 mg
Vitamin C     240 mg
Vitamin E*    100 IU minimum per day
Green Tea Extract     200 mg
Silymarin (Milk Thistle)     150 mg
Ginkgo Biloba     50 mg
Lycium (Goji Berry)*     200 mg

* Goji Berries are often referred to as the world's most nutritious foods. They are noted for their powerful antioxidant benefits, having 500 times more Vitamin C than an orange (compared ounce per once), more beta carotene than carrots, and are loaded with essential fatty acids, 18 amino acids and 21 trace minerals.

By educating your clients on the value of proper diet and supplementation you are teaching them ways to maintain their skin and promote over all health. You will achieve even better results from your professional services and home care recommendations.

It's 1:20 pm and Karen, a long-time client is late, yet again, for her 1:00 treatment. She rushes in, drops her things and collapses in your chair saying, "It's been a crazy day, please help me relax." You guide her through a few deep breaths, when her cell phone rings. She turns it off. You begin again. While her time is cut short, you do your best to provide excellent service. When her mask is on you reach for your Blackberry to check in with your son's teacher. His report card is being emailed to you. You open it, gasp at the grades and think—how can he get into college with these grades?  Your heartbeat accelerates. You are distracted. All you can think about is finishing with your client so you can call the school. In the meantime, a note from the receptionist slides under your door alerting you that the computer system has gone down and the remaining appointments for the week have been deleted — PLEASE COME TO THE FRONT DESK AFTER YOU ARE FINISHED…

If you can relate to this scene, you are experiencing a new type of stress which I have coined, "Cultural Stress." Cultural stress is pervasive stress and it thrives in today's world. The word stress as it relates to emotions became part of our vocabulary in the 1950's. It originated with the onset of the Cold War. During this time, we had a fear of atom bombs so we built bomb shelters; but as a society, we could not say we were afraid, therefore we called it "stress."

In the years since then, stress has evolved. Cultural stress started infiltrating our lives 20 years ago, as we became more technologically savvy and prosperous. And it doesn't affect only adults - cultural stress starts young and is initiated by parents. New parents are often anxious about getting their child into the best preschool. In fact, it's common for unborn children to be placed on a preschool wait list. The next focus is on ensuring that the child is enrolled in all the right extra-curricular activities — from preschool through high school. This cycle puts pressure on children to excel at a very young age, while placing a burden on the parents to make more money to pay for the education and extra-curricular activities.

This scenario coupled with our society's increasing affluence has a far-reaching domino effect. In order to make more money to pay for all the activities we are involved in, we are working longer hours. According to a U.S. government report, Americans now put in more hours on the job — an average of 47 hours per week —than workers in any other industrial nation.

The more money we make, the more things we buy and this phenomenon extends well beyond possessions. As we have become a more informed society, we are more aware of the endless possibilities available to us in the form of clubs, lifestyles, diets and leisure activities, to name just a few. All of this has put a great strain on our health and well-being, especially since the vast majority of us are barely keeping up.

As a result of this pursuit to stay ahead, people are experiencing extreme levels of on the-job stress. According to the federal government's National Institute for Occupational Safety and Health, 40% of workers find their jobs stressful, and 75% of people surveyed believe their jobs are more stressful now than a generation ago.

Our busy, on-the-go lives have created yet another problem. We have no time to cook at home, and so we have grown accustomed to eating out. Those who eat in restaurants are faced with the stress of choosing a restaurant and making a reservation or sometimes waiting an hour or more for a table. Others become reliant on unhealthy fast-food meals, as a matter of fact The American College of Nutrition reported that 46% of expenditure on food items was spent on unhealthy fast food. In either case, we are consuming more processed foods than ever, and eating foods high in sugar and saturated fats. This can cause glycation, making us more susceptible to diabetes. Refined foods also contribute to poor brain function and depression, and we often combat this with caffeine to stay awake and prescription sleep aids to help us sleep. Our national sleep deficit has resulted in an astounding 42 million prescriptions in sleep aids in 2005, and over $9.2 billion in retail coffee sales.

To help maintain mental and physical health, we need to eat complex carbohydrates from whole grains, fruits and vegetables —and good fats, especially Omega-3 Fatty Acids. These not only encourage water to be attracted to the cells, but are also a component of the cell membrane. In fact, recent studies have shown that Omega 3's in our food may help decrease depression — a leading mental health disorder that has been linked to the constant and pervasive stress in our lives.

Cultural stress and your clients' skin
As we who work with the skin know, all these conditions are reflected in the way the skin looks and feels.

How does cultural stress affect your skin? First of all, any kind of stress causes a tremendous amount of nervous system activity. It can cause an outpouring of adrenaline, cortisol and other stress-related hormones. In recent years, I have observed an increase in rosacea and adult acne, which I believe are directly related to an increase in cultural stress. When you are stressed, researchers believe that the increase in certain hormones known to worsen acne, are released.

Another skin condition that I believe may be attributed to cultural stress is an increase in facial hair among adult women. Hormonal shifts and the outpouring of androgens when you are stressed can cause you to lose hair, and it can also cause hair to suddenly appear in places where it didn't previously exist.

The good news is we can counteract cultural stress and improve our health both physically and emotionally with the " Water Principle®." Cultural stress contributes to damaged cell walls which in turn, allows the precious water that keeps them functioning to escape. The water loss has a myriad of effects. It causes our cells and connective tissue to break down, which prevents our heart, lungs, brain and other organs from functioning at optimal levels — all of which become apparent when you look at the skin.

We can encourage more water in the cells and reduce cultural stress by addressing these 3 areas, and best of all — you can teach these simple steps to your own clients:

TOPICAL CARE
?As the largest organ of the body, the skin is extremely responsive to topically applied products. By using the appropriate skincare regimen and professional spa treatments, you can address skincare concerns ranging from acne to wrinkles, while also preventing future damage.

INTERNAL CARE
?With topical skincare, we address approximately 20% of the skin, the epidermis. The remaining 80%, the dermis, responds by feeding the skin from the inside. Encourage your clients to eat a diet rich in raw fruits and vegetables and healthy fats such as those found in raw nuts and olive oil to promote healthy, hydrated cells. Recommend a dietary supplement to provide the body with a constant supply of essential nutrients.

EMOTIONAL CARE
?Maintain connections with others, discover a passion such as painting or dancing. Reducing isolation promotes a healthy sense of self. In your treatment room, you are providing one of the most powerful tools for emotional care, the healing power of touch. Research from the renowned Touch Research Institute shows that it's as beneficial to touch as it is to be touched. Massage is shown to increase weight gain in premature infants, alleviate depression, and positively alter the immune system.

Cultural stress, whether caused by fear, overwork or too many options causing conflict in decision making, ultimately leads to isolation. I believe isolation to be one of the most prominent diseases in today's world. Studies have shown that to reduce isolation, people need to have regular physical and social contact which reduces cultural stress, leading to happier, healthier lives.

You, as an esthetician are a healthcare provider. You are in a unique position to help your clients reduce the symptoms that come from cultural stress and achieve a healthier state of well-being. According to the International Spa Association, the spa lifestyle has become the fourth largest leisure industry in the United States, evidence that more people are turning to spas to relieve stress and promote overall health.

It's important to understand cultural stress and its pervasiveness. Keeping this concept in mind is a necessary step in creating a spa atmosphere that is completely free from the factors that can contribute to cultural stress, including cell phones, PDA's, televisions and loud music. The spa environment should be focused on creating the optimum healing environment.

Also, we want to simplify the remedies we prescribed to clients. Often times, we get so caught up in the solutions to our client's problems that we can actually overwhelm them and make the problems worse. If we keep the message simple and focus on the client's main issue of concern, be it sun damage, acne, muscle tension, or anything else, the treatment becomes much more palatable and the client is more likely to embrace and benefit from it.

Another simple way to help ease the weight of cultural stress is to make our clients aware of the problem. Most people are feeling this tension without even knowing what it is. Once our clients are aware of its existence they can begin to take steps to combat the problem and become more healthy, balanced and relaxed.

Cultural stress is a part of life. It's something that affects all of us, but it doesn't have to overtake our life. While your clients may initially come to you with a skin condition, they ultimately come back to you because you do more than just care for their skin. By helping your clients develop tools to cope with the cultural stress in their life, you will be giving them a benefit that they will see on their skin — a benefit they will also feel physically, internally and emotionally.

Tips for reducing cultural stress

Practitioner Heal Thyself
The first step in reducing cultural stress is trying to determine what gets you worked up. Identify in yourself the biggest causes of cultural stress and then develop a plan of action to reduce the impact it has on your daily life.

Practice being mindful
Take some time each day to meditate or be quiet, and enjoy the simple rhythms of life.

Use 5-cent psychology on yourself
Most of us have cell phones. If you are stuck in traffic and late for an appointment, make a call and then accept the fact that you can't control the situation. One thing you can control is how you react to these situations. Try to make the best of it, as I always say "why have a bad day when you can have a good day."

Exercise Regularly
Go for a walk, do yoga or take an exercise class. Being physically active, even for just a few minutes can make a difference in the way you feel.

Nourish your body for optimum health
Make it a habit to avoid the Standard America Diet. Get foods that encourage and increase the water content in your body — a diet full of whole grains, fresh fruit and vegetables, good fats and proteins. Take a nutritional supplement to fill the nutritional gaps in your diet. And remember the " Water Principle®".

Get a good night's sleep
Americans sleep less than people in any industrialized country in the world. You need seven to nine hours of sleep every night to fully restore the body. Don't lose sleep, find the time to recharge your body at night so you have the energy to face the challenges that come up every day.

Find a hobby
It forces you to take time out for yourself and do something enjoyable, while providing time for you to reflect.

The goal should be to reduce cultural stress and while enjoying the simple pleasures of life. As the great English poet William Wordsworth wrote:

The world is too much with us; late and soon,?Getting and spending, we lay waste our powers:?Little we see in nature that is ours….

Section 1: Environmental Aging
Section 2: Free Radicals vs. Topical Antioxidants
? Section 3: Vitamin C
Section 4: Pomegranate
Section 5: Antioxidant Auxiliary
Section 6: The Future Antioxidants

Environmental Aging
Since I began practicing medicine in 1972, I have been studying the ability of antioxidants to repair and protect the skin. Witnessing first hand the effects of sun exposure, pollution, smoking, alcohol and stress on my patients’ skin led me to study the role of antioxidants in environmental aging. The difference between the aging of a sequestered monk and that of a farm worker the same age was not only visibly astounding, it also supported my belief that while biological aging is inevitable, environmental aging is widely preventable.

Antioxidants have made their way front and center into the eye and mind of the consumer. These miracle cell protectors represent the front line of defense in the war against environmental aging. As the professional skincare industry continues to explore the role of antioxidants, we are entering an exciting time to both educate, protect, and deliver our clients and patients advanced products to address a wide range of skincare concerns and slow the effects of environmental aging.

Free Radicals vs. Topical Antioxidants
Each and every day, the human body’s largest organ, the skin, is bombarded with environmental assailants resulting from exposure to smoke, pollution, and most importantly, ultraviolet radiation from the sun. This is in addition to the one thousand hits each cell sustains by free radicals generated by the body’s own metabolism. In the skin, free radicals trigger the release of inflammatory mediators, breaking down collagen and damaging cell barrier. In addition to this external damage, free radicals are one of the main factors contributing to the formation of cancerous cells.

Luckily, it is possible to literally boost the skin’s external defenses against harmful free radicals and control environmental aging by applying antioxidants topically. Countless studies have proven that antioxidants applied to the skin’s surface offer protection from sun damage and stimulate collagen production. The most powerful and potent of these topical antioxidants are Vitamin C and Pomegranate.

Vitamin C
Vitamin C is a multi-tasker for the skin. It prevents water loss, helping to maintain the skin’s barrier function, while building collagen and elastin. Furthermore, Vitamin C deactivates the unstable free radicals, preventing much of their potential damage. There is also increasing evidence that Vitamin C shields the skin from the sun’s burning rays, especially when it’s applied in high concentrations or combined with vitamin E, sunscreens, and skin soothers.

Today, we have learned much about topical preparations of Vitamin C. Cosmetic chemists must carefully regulate the percentage concentration and delivery system, as these crucial variables determine the effectiveness of the product. I have spent many years working to develop an over-the-counter, highly concentrated, stable vitamin C product that consumers can easily use at home.

Vitamin C is actually quite delicate. It is water soluble, but when mixed with water and exposed to oxygen it fails to maintain antioxidant activity. In addition, Vitamin C rapidly disintegrates when exposed to light. After much painstaking work, I developed and patented a technology that uses a highly concentrated form of Vitamin C in a water-free lotion. It’s a rich, soothing cream that can deliver pure Vitamin C to the upper layers of the skin without irritation and in consistently high amounts. Over the years since this discovery, research has shown that repeated use of Vitamin C is best, as this builds a reservoir of Vitamin C on the skin.

There are also “mix and use” products that involve mixing Vitamin C into a base or vehicle and applying it immediately while the Vitamin C is still active. I find these products to be extremely effective, especially for higher concentrations of Vitamin C that physicians or estheticians can safely deliver to the skin. I do not recommend such high concentrations for consumer use. Topical products containing safe levels of Vitamin C are widely available to today’s consumers, delivering antioxidants to skin with both cosmetic and protective effects.

Pomegranate
The ellagic acid found in pomegranate fruit is the most recent addition to my antioxidant army. I first became interested in ellagic acid as I studied polyphenols, which is the active compound that gives the pomegranate its antioxidant energy. Not only is ellagic acid one of the most potent antioxidants, effectively scavenging free radicals, it also stimulates an increase in the body’s own built-in antioxidant, glutathione.

Pomegranate (Punica granatum L) is a native plant of Northern Africa, and one of the oldest natural remedies known to man. P granatum was mentioned in the papyrus Ebers of Egypt written in about 1550 BC. Hippocrates described its medicinal powers. Doctors in Greece prescribed pomegranate juice as a remedy with multiple activities: anti-inflammatory; as a potent anthelmintic (acting to expel or destroy intestinal worms), chronic diarrhea, dysentery, and cough suppressant.

Perhaps the most extraordinary benefit of this radically innovative ingredient is that it actually boosts the SPF rating of topical sunscreens so that the same SPF protection levels are maintained using less chemicals and more antioxidants. Research shows that ellagic acid, found in pomegranate juice has the strongest age-proofing capabilities to date and is currently being studied for its anti-cancer and healing benefits.

In a recent South Dakota State University study entitled Chemopreventative Effects of Pomegranate Seed Oil on Skin Tumor Development, Pomegranate extract was applied topically to topical skin tumors on mice. After five weeks, the study concluded that topical application of pomegranate oil inhibited papilloma incidence and activity.

The protective and healing properties of the Pomegranate are increasingly important today, as the rate of skin cancer is increasing faster that any other cancer among Western countries. Topical application of ellagic acid found in Pomegranates is so effective at preventing sun damage that I added it to all of the products in my suncare line.

Antioxidant Auxiliary
In addition to Vitamin C and Pomegranate, other powerful antioxidants such as Vitamin E, Coenzyme Q 10, Grapeseed Extract, and Alpha Lipoic Acid are powerful allies in the war against free radicals. When used before sun exposure Vitamin E reduces redness and swelling of the skin, results in less destruction of lipids, and fewer sunburn cells. When Vitamin E and Vitamin C are combined in high concentration, topical products offer amplified sun protection.

Standardized extracts of green tea and grape seed are other powerful antioxidants included in many of my products. Like Vitamin C and Pomegranate, these are truly multipurpose agents. Grape seed extract, for instance, not only disarms free radicals, studies have also shown this antioxidant to reinforce the structural fibers of the skin, collagen, and elastin.

Coenzyme Q 10, also known as ubiquinone, and Alpha lipoic acid help to protect the skin from sun damage by suppressing the production of the collagen-destroying enzyme, collagenase and evidence supports that topical use of Coenzyme Q 10 penetrates between cells.

The Future of Antioxidants
The role of antioxidants in both anti-aging and protective topical products has become a hot-button topic. Amongst the aging baby boomer generation, topical antioxidant products are increasingly in demand, both to reverse damage accumulated over years of exposure to the sun, dehydration, and environmental assailants and to protect skin from the harmful effects of such environmental pollution. I have also noticed a preventative trend resonating in Gen X and Gen Y’ers, who are adopting anti-aging skincare regimens (as early as 20 years of age), in an attempt to thwart signs of aging and protect skin from environmental damage before the tell-tale signs of aging emerge.

Perhaps the most exciting development of all is the mainstream understanding and demand for antioxidants and SPF in topical skincare products. Today’s average consumer is well versed and educated as to the effects of environmental damage, both from a cosmetic and a wellness perspective. As a result, ingredients such as Vitamin C and Pomegranate are becoming increasingly integral components of skincare and SPF has been widely included into cosmetic products. More and more, customers are adopting proactive paradigms about their bodies and overall wellness, becoming savvy about the benefits of Vitamin C and Pomegranate. Consumer knowledge and education translates directly to the esthetician and spa professional, as the demand for such antioxidant rich treatments escalates by the day.

As skincare professionals continue to research and develop advanced antioxidant technologies, we enter into an exciting period where dermatologists and estheticians can offer the consumer the cosmetic effects of beautiful, wrinkle free skin while providing valuable, life saving protection against environmental damage.

Dr. Murad is a researcher, Board-Certified Dermatologist, pharmacist, Associate Clinical Professor of Dermatology at the David Geffen School of Medicine at UCLA and CEO of Murad, Inc.

July 12, 2005 — It hits the thighs, buttocks and tummy — and sometimes strikes the upper arms as well.

The culprit? Cellulite — lumpy, bumpy-looking skin that can make even a well-shaped female body flabby and old.

Often viewed as an inevitable sign of aging, cellulite resists dieting and even exercise. That's because it's a skin problem — caused by the layer of fat below the dermis that sneaks its way up toward the surface of the skin and wreaks rippled havoc.

Lately, a host of treatments — lasers, radio waves and topical creams — have been aimed at cellulite, turning mushy skin back to its firmer, younger days.

And one of the newest approaches suggests the solution may lie as close as your refrigerator.

Dr. Howard Murad, a Los Angeles dermatologist whose clients include Brooke Shields, Uma Thurman and Cheryl Tiegs, says the best way to defeat cellulite is to "feed">the skin with nutrient-dense foods and supplements.

"Cellulite is not a fat problem, it's a skin cellular problem," Murad says. "You can have total liposuction and get rid of every bit of your regular fat and still have cellulite — you can exercise until the cows come home, it isn't going to help."

What does help, he writes in his book, "The Cellulite Solution: A Doctor's Program for Losing Lumps, Bumps, Dimples and Stretch Marks" (St. Martins Press, $24.95), is eating foods rich in nutrients like lecithin, essential fatty acids, amino acids and antioxidants. These are the foods, he says, that reduce cellular inflammation, squeeze out excess fluids and, most important, increase circulation, which prevents fat cells from migrating to the surface and looking like cottage cheese.

Why Cellulite?
According to the American Academy of Dermatology, cellulite is primarily a female problem because a woman's body is designed to store extra fat cells, ensuring adequate calories for pregnancy and lactation. Those cells are stored primarily in the buttocks, thighs and sometimes the stomach and upper arms — all the places where cellulite is most apt to appear.

Just how much your skin dimples is largely due to genetics, since that's what determines the number of elastic, collagen-rich fibrous bands called septa that naturally surround fat cells and keep them in place — at least when a woman is young.

The problem is, with aging, the septa can become rigid and hard. A drop in collagen and other natural chemicals can decrease that elasticity, so the bands can no longer keep fat cells in their place.

Eventually they push up through spaces in the hard septa, landing just below the surface of your skin.

And there it is — that cottage cheesy-looking surface we call cellulite. And it's spawned a veritable industry to fight it.

Last year, the Food and Drug Administration approved TriActive, which attacks cellulite with a combination of radio frequency energy and infrared light to melt away the underlying fat, allowing top skin to lie smoother.

Just this June, the FDA approved VelaSmooth, a similar device that emits a higher level of energy. Ten treatments cost around $2,000, and results are said to last about six months.

Murad argues a dietary approach works better because it attacks the problem at the source. By restoring microcirculation to skin cells, helping the body build more collagen and deliver key nutrients like glucosamine to skin cells, septa bands start behaving more the way they did back when you were young and cellulite-free. The end results, he claims, last longer than other treatments.

He says independent labs confirmed that his regimen — a combination of diet, nutrient supplements and exfoliation treatments totaling about $215 — yielded a 78 percent increase in firming, as well as a 47 percent reduction in stretch marks within 12 weeks. Visible results were apparent in eight weeks.

Dr. Amy Newburger, a dermatologist and director of Dermatology Consultants of Westchester, agrees that the dietary approach makes sense. But she says you can get similar results for less money with a good multivitamin and over-the-counter caffeinated creams instead of Murad's more costly supplements and serums.

"Just eat more fruits and vegetables and reduce junk food, which will reduce fluid retention, immediately improving cellulite," she says. "[And] take a good multivitamin like Centrum and an essential fatty acid supplement to keep connective tissue and skin healthy."

She recommends a caffeine-rich cellulite cream, which she says has been proven to work by aiding in fat burning and reducing fluid retention.

If all else fails, never underestimate the power of a good beach cover-up.

If you want to eat your cellulite away, as Dr. Howard Murad suggests, fill your shopping cart with the following:

Lecithin: eggs, soy, cauliflower, peanuts, peanut butter, oranges, potatoes, spinach, iceberg lettuce, tomatoes.

Essential fatty acids: flax seed, olive and canola oils, ground flax, sunflower or hemp seeds, raw nuts like walnuts, almonds, cashews, Brazil nuts, pistachios, tuna, salmon.

Amino acids: berries and citrus fruits such as oranges and grapefruits.

Polyphenols: raspberries, strawberries and pomegranates.
* Antioxidants: all fruits and vegetables, especially fresh or dried goji berries (also called wolfberries). A powerhouse of vitamins, goji berries (which look like tiny grapes and, when dried, red raisins) are available in most Asian markets and health-food stores.

For press inquiries, please contact:
Jennifer Newton | jnewton@murad.com

Spa Finder Presents 2005 Visionary Award to Howard Murad, M.D. Leading Spa Marketing Company Honors Anti-Aging Skincare Pioneer and Founder of Medical Spa Concept

NEW YORK--(BUSINESS WIRE)--Feb. 28, 2005--Spa Finder, Inc., the world's largest spa publishing, Internet, gift certificate and marketing company, has awarded its third Visionary Award to Howard Murad, M.D. Dr. Murad, founder of the Murad Medical Spa and creator of the popular line of Murad skincare products, was honored for his breakthrough work in the area of anti -oxidant/anti-aging skincare, and for his seminal role in establishing the medical spa concept. Spa Finder Chief Marketing Officer Sallie Fraenkel presented the award to Dr. Murad during a ceremony held at the Reed Spa Expo in Los Angeles. The Visionary Award is given annually to an individual who has made outstanding contributions to the development of the?medical spa industry.

For decades, Dr. Murad has been at the forefront of a true skin care revolution, helping to guide us from a superficial, cosmetic approach into a new era of total skin health," said Fraenkel. "He was also the first individual to bring clinical medicine into the spa -- a model that's now helping countless people live healthier, happier lives." Dr. Murad founded the first medically supervised day spa, "A Sense of Self" (now the Murad Medical Spa), in 1988, establishing the blueprint for what has come to be known as the medical spa. According to Spa Finder's new Medical Spa guide, there are now more than 500 medical spas throughout the U.S., making medical spas one of the fastest growing segments in the spa industry. "Nearly two decades later, Dr. Murad's vision of offering medical treatments and services in a spa setting is exploding into the American mainstream," said Fraenkel. "It's a concept that's affecting positive change in both the worlds of spa and traditional medicine."

Throughout his career, Dr. Murad has helped pioneer a number of breakthroughs in the fields of skincare and dermatology. He created some of the very earliest cosmeceuticals, in the late '80s. He was also one of the first doctors to formulate professional-strength exfoliating alpha hydroxy acid treatments, as well as one of the first to utilize antioxidants (including pomegranate) to treat environmental damage and the signs of aging and to stabilize Vitamin C to treat environmental damage and unwanted pigmentation. Because of these and other innovations, he is generally acknowledged as the "father" of Internal Skincare, which is based on formulating combinations of antioxidant vitamins and other nutrients scientifically targeted to specific skin conditions.

Dr. Murad has written numerous books detailing his skincare philosophy, including "Wrinkle-Free Forever," and recently debuted his program in his Inclusive Medical Practice, Next Generation Wellness Center, a dedicated state-of-the-art research facility located within the Murad global headquarters.

His El Segundo, CA medical practice, the Murad Medical Group, has a patient base of nearly 50,000 people.

"It's difficult to imagine anyone who has sparked such profound changes in the way we approach beauty, health and wellness," added Fraenkel. "Spa Finder is proud to present our Visionary Award to a true spa industry visionary."

For press inquiries, please contact:
Jennifer Newton | jnewton@murad.com

As a practicing dermatologist for over 30 years, I have treated nearly 50,000 patients caring for the most basic of skin concerns such as aging skin, dryness, and sensitivity to the more severe diseases of acne, rosacea, and skin cancer. Regardless of the concern, there is a common thread that runs through them all — WATER LOSS.

The Water Principle Primer
?Using the experience and knowledge I’ve gained through years working in the fields of science and medicine I developed a revolutionary theory that has become known as “The Water Principle.” It is the basis for all of my healthy skin programs. When our cells are not fully hydrated they cannot function at their optimal level. This leads to much of the tissue damage that we call aging. For example, dehydrated skin is more likely to weaken and succumb to all sorts of ravages that lead to wrinkles, loss of elasticity, dryness, redness and many other problems. This dehydration and deterioration of our cells can be due to a simple deficiency in our diets of vital cell-hydrating nutrients.

Many people believe that drinking eight, ten or more glasses of water a day is the answer to hydration, but The Water Principle is not about drinking water, it’s about getting water into the cells and keeping it there so that every cell can function to its full capacity. Next to oxygen, water is the most important substance you need, and almost everything we know about aging tells us that the decline in function over the years is a direct result of water loss. For most people the problem is not that we don’t drink enough water, its’ that we are unable to keep the water we drink within in the cell walls.

As we age, our bodies lose the ability to utilize water as they did when we were younger. Over time, our cells and the other areas of our bodies that need hydration break down and become unable to hold onto water, leaving them weakened and less effective. This water that your cells can no longer utilize now passes right through you, or even worse, stays in between the tissues of your body, swelling up your ankles or puffing up your eyelids. I call this wasted water, and if we are to attain healthy skin, we need to put it back in our cells where it will keep us firm and supple.

Think of a newborn baby. As an infant a baby’s body weight is 75% water, with skin that is smooth and resilient. Now think of an adult. By middle age the average male can contribute about 60% of his total weight to water, and the average female 50%. As we age, we loose water inside our cells and tissue. Skin becomes dry, thin and rough. Drinking water alone is not the solution to replenish this rapid decline in water. You need to repair the tissues in your body that are losing it.

The Two Types of Body Tissue
As I have come to understand the body in a broad way, I realized that there are truly only two types of tissue. They are:

Cells: Though skin cells are not the same as say, liver cells, their basic traits are the same:
All cells have a membrane or protective wall comprised of lipids, or fats, and lecithin.

Within this cell wall is a substance called cytoplasm, and with the cytoplasm is the cell’s nucleus. The nucleus is the control center, or brain, of the cell. Both the cytoplasm and the nucleaus are predominately made up of water. Connective Tissue: This is the tissue in your body that has very few cells and is predominately made up of fibrous material that connects the various organs to the rest of the body.

Connective tissue is comprised of:
The body’s Matrix (also known as Glycosaminoglycans or GAGs) – This is a semi-solid matter made of materials such as hyaluronic acid, a water-loving substance that can actually attract up to 1,000 times its weig ht in water. The building block for hyaluronic acid is glucosamine. Collagen and Elastin – These keep the connective tissue firm and hold its shape. The building blocks for collagen and elastin are the amino acids in the foods we eat.

The two types of tissue throughout the body:
The heart is made up of cells. The blood vessels are connective tissue. The brain is made up of cells. The nerves are connective tissue. The bones are made up of cells. Tendons and ligaments are connective tissue. The epidermis is made up of cells. The dermis is connective tissue.

To make positive long lasting changes in the skin, it is vital to strengthen and hydrate the cells and connective tissue by feeding them with the nutrients need to stay they need to attract and hold onto your body’s water.

Hydrating Cells Internally
By taking the necessary supplements every day and making a few changes to our diet we can reverse the breakdown of our skin and prevent future damage. I have been using a combination of cell repairing nutrients such as glucosamine, lecithin, and essential fatty acids for years with amazing results. Through numerous studies, I have proven that by incorporating the Water Principle into my patients’ treatments, made miraculous changes in their wrinkles by smoothing and firming the skin. Patients with acne healed faster, with a great reduction in breakouts. Eczema patients no longer suffered from the severe dryness and irritation that plagued them, and even cellulite and stretch marks became diminished through the inclusion of The Water Principle.

Key Nutrients To Take
?I have always said, "before there were medicines, there were foods". Eating the appropriate amount of cell hydrating and connective tissue building foods is the ultimate way to feed the skin, however taking a dietary supplement on a daily basis is a guarantee you will maintain the correct levels of nutrients in the body at all times.

As the creator of Internal Skincare back in 1995, I have proven through independent scientific studies that it is possible to reduce wrinkles, increase elasticity, clear acne increase sun protection, and reduce cellulite with specific supplement formulations. Below is an example of key nutrients that optimize the water content in the cells while also building and strengthening connective tissue:

Glucosamine to increase the water content and help strengthen the dermis. Amino Acids to encourage the healthy formation of collagen and elastin tissue. Phosphatidylcholine and Lecithin to maintain cell walls.
Antioxidants including Pomegranate Extract, Goji Berry Extract, Vitamins C and E, Grapeseed Extract, CoEnzyme Q10 to protect against free radical damage to cell walls and connective tissue.

Essential Fatty Acids such as Flaxseed Oil and Fish Oil to lock moisture in the cells.

Anti-inflammatory ingredients such as Zinc, Aloe Vera and Curcumin to soothe skin irritation.

When taken in the right combination, you can increase the water content of your cells, and reduce wrinkles by 34% and increase skin elasticity by 18% in only five weeks!

Daily Diet
?In addition to the dietary supplements, you can maximize your healthy skin benefits with foods. Below are tips on encouraging The Water Principle through diet:

Make the time for a healthy breakfast every day, even if it’s just some fresh fruit to boost your antioxidant levels.

Water is essential – and can come from several sources including food. Decaffeinated herbal teas, vegetable broth, fruit juices, and fresh fruit and vegetables count towards your daily water intake. In fact, I believe that the best sources of water are fruits and vegetables. A good barometer of whether your body needs more hydration is if your lips are dry.

Eat one to two eggs per week. They are an excellent natural source of protein, Folic Acid, vitamin A, lecithin, and B-12. Be sure to eat the yolk as well as the white of the egg because the yolk contains the lecithin.
Fruits and vegetables lose water and nutrients the more they are cooked. Stick with foods as close to their natural state as possible —avoid over cooking, boiling, or heating whenever you can to preserve the pure nutrients in whole food.

Three-Pronged Approach to Overall Health
At my research center, I have documented additional health benefits that go above and beyond skin improvement. After incorporating The Water Principle into their life, some of the most impressive changes besides skin improvement including a reduction in high blood pressure, healthier gum tissue, increase in scalp hair, and breast cancer patients reported reduction in lymphodema just to name a few. My recommendation for maintaining healthy water in the cells and connective tissue incorporates a three-pronged approach:

1. Topical Skincare — utilizing topical products that encourage healthy cell turnover plus a mix of antioxidants, anti-inflammatories and hydrating ingredients. These include:?    i. Antioxidants — Vitamins C, E, Grapeseed Extract, Pomegranate Extract, Goji Berry Extract?    ii. Anti-Inflammatories — Licorice Extract, Zinc, Chamomile and Tiger’s Herb?    iii. Hydrators — Sodium PCA, Hyaluronic Acid, Evening Primrose Oil and other plant based lipids

2. Internal Skincare — taking key nutrients thru supplements and foods that repair the cell wall, and attract water, plus nutrients that build connective tissue.

3. Inclusive Health — caring for one’s self through incorporation of massage, aromatherapy, personal interaction and creating a general passion for life. Scientific studies have proven a link between our mental health and happiness, and physical health and hydration.

Conclusion
A healthy complexion is a reflection of total wellness, both inside and out. This in turn, creates a healthy environment for the skin so if problems do arise, they resolve more easily. Furthermore, skin care can lead the way to overall health. Take all the necessary steps to achieve healthy skin – the right products, the proper nutrients, and positive lifestyle choices – and your whole body will be healthier.

As Nobel Prize Winner, Dr. Alexis Carrell has said, “The cell is immortal. It is merely the fluid in which it floats that degenerates. Renew this fluid at regular intervals, give the cells what they require for nutrition, and as far as we now, the pulsation of life can go on forever.” Water, truly is The Essence of Life.

Three-Step System Simplifies Daily Acne Regimens
Acne affects nearly 17 million people in the United States, and frustration is common among many individuals when looking for effective treatments. Acne-management regimens can often be expensive, with little or no promise of results. The new Murad Acne Complex® Kit, a four-product, three-step, system has streamlined the steps to attacking acne. Ideal as an introductory system for teens beginning an acne regimen or for individuals combating adult-acne for the first time, this kit delivers!

"Acne blemishes can scar the skin, not to mention one's self-esteem," explains Howard Murad, M.D., dermatologist, CEO and founder of Murad Inc. "I created the Acne Complex Kit to prevent this damage. This kit is a special system that caters to the varying skin types – so that the acne can be effectively treated."

Breaking the vicious cycle of acne breakouts, the Acne Complex Kit, uses the patented, proven Murad formulation to combine powerful and successful treatments into a simple, daily regimen. The first of its kind, the Murad acne products are clinically proven to help rid the skin of pimples, whiteheads, blackheads, redness and inflammation - leaving skin clear, smooth and healthy looking.

The Murad Acne Complex Kit consists of:
Clarifying Cleanser (4.5 fl. oz) – Salicylic Acid deeply cleans pores while Triclosan reduces 99.9% of surface bacteria, the contributing factor for red bumps, in one minute. Salicylic Acid deeply cleans pores, while anti-inflammatory agents such as Black Cohosh and Green Tea Extracts combine with natural moisture factors to soothe and hydrate.

Exfoliating Acne Treatment (2 fl. oz) – Alpha and Beta Hyroxy Acids gently exfoliate, while Retinol, Zinc, Arnica and Hydrogen Peroxide control oil, reduce bacteria, alleviate redness and prevent new breakouts. Patented formula (U.S. Patent #6,071,541) is clinically proven to reduce blemishes by 40% in four weeks.

Acne Spot Treatment (.5 fl. oz) – Sulfur minimizes the severity of breakouts, while Grape Seed, Zinc and Licorice Extract soothe irritation and reduce redness. Fast-acting spot treatment for all skin types.

Skin Perfecting Lotion (1.5 fl. oz) – The newest weapon in Murad's acne management arsenal. This unique formula minimizes breakouts and controls shine while delivering oil-free hydration, with a lightweight finish, to problem skin. Retinol retexturizes skin as it encourages healthy cell turnover. Extracts of Arnica, Willow Herb, Grape Seed and Green Tea soothe and protect inflamed skin.

The Murad Acne Complex Kit is approximately a two-month's supply of product, and includes an instructional brochure on how to use to regimen.

For press inquiries, please contact:
Jennifer Newton | jnewton@murad.com

Show some leg! Murad's NEW Firm and Tone Serumvisually minimizes imperfections and reduces the appearance of cellulite and stretch marks by masking and refining uneven skin texture to improve skin firmness and elasticity.

Three key ingredients come together to topically firm and tone body contours for a refined silhouette:

Uncaria Tomentosa Extract (Cats Claw) - Extract from the Amazonian forest, provides anti-inflammatory benefits while penetrating skin tissues to reduce cellulite structure.
Esculin (Horse Nut Tree Extract) – Quench free radical damage and stimulate blood flow to restore skin firmness and smoothness.
Capsicum Fruntescens Fruit (Cayenne Pepper) – Stimulates blood vessels to increase circulation.

This formula improves overall appearance of skin up to 80% by reducing the appearance of cellulite by up to 69%, increasing skin firmness and elasticity while masking imperfections.

"It is a breakthrough serum containing encapsulated liposomes that deliver actives to skin tissue layers, assisting with reversing and preventing cellulite and stretch marks,"explains Dr. Howard Murad, dermatologist, CEO and founder of Murad Inc. and author of Wrinkle-Free Forever. "Designed to hydrate and exfoliate, the Firm and Tone Serum allows for tight, supple, smooth skin that demands to been seen."

Used in conjunction with Murad's NEW Firm and Tone Dietary Supplements, the combination allows the skin to function at its highest level. The result is maximum cellulite and stretch mark prevention, firmer, more resilient skin and the prevention of future damage.

For press inquiries, please contact:
Jennifer Newton | jnewton@murad.com

Delicate eye tissue taking a beating? Treat and repair pigmentation and damage caused by overexposure to environmental elements with Murad's NEW Lighten and Brighten Eye Treatment! Years in development, this new formula is the only one scientifically proven to fight multiple signs of distress around the delicate eye area by lightening dark under-eye circles by an average of 59% and diminishing under-eye bags and puffiness by up to 50%.

"This patented, triple-action formula targets the signs of environmental damage around the eye area by lightening dark circles and neutralizing the most abundant pollutants. It addresses puffiness and under-eye bags with key ingredients that combat signs of intrinsic aging," explains Dr. Howard Murad, dermatologist, CEO and founder of Murad Inc. and author of Wrinkle-Free Forever® and The Cellulite Solution®. "The benefits of Hydroquinone, which lightens the skin and diminishes the appearance of dark circles, and Palmitoyl Tetrapeptide-3, which reduces puffiness and bags under the eyes due to fluid build-up caused by poor circulation, come together for optimal eye care and repair."

The extensive, independent research on this product is outlined below.

Objective
This study was conducted to determine the efficacy of Murad Skin Lighten and Brighten Eye Treatment in lightening and brightening under-eye skin.
The study was an eight (8) week use study with each subjects' baseline scores serving as the control.
Performance was measured visually and instrumentally using a Chroma Meter. Forty-two (42) subjects were enrolled and forty (40) subjects completed the study.
One (1) week prior to the start of the study (Day -7), the prospective subjects with prominent under-eye discoloration visited the test site, where they completed a brief medical history and voluntarily completed the informed consent.

They were given instructions for the qualifying "washout" week. The "washout" instructions advised them to discontinue the use of any skin lighteners.

They were instructed to:
Use their regular cleanser for all facial washing over the next week.
Return to the test site at the following week for qualification. On all exam dates, they were to refrain from using any cosmetics, except lip products.
The use of moisturizers was permitted

After each person was evaluated they were issued appropriate product and study instructions. The instructions informed the subjects that:

They were not to use any "skin lightening" products other than the test product for the eight (8) weeks of the study.
They were to apply the product one (1) time daily, to the designated areas before applying make-up. The product sites were not washed again for at least two (2) hours after application of product.
They were to return for additional evaluations at four (4) and eight (8) weeks and at these times they were not to wear cosmetics.
If they had any questions, they were to contact the study coordinator.

Upon their return at weeks four (4) and eight (8), participants were evaluated and scored as noted previously. At weeks four (4) and eight (8) they were given an evaluation questionnaire supplied by Murad, Inc. Any subject who discontinued from the study, after starting the study, due to an adverse experience was considered a completed case. Subjects who dropped due to treatment failure were not considered completed cases.

Conclusion Under the conditions employed in this study, Murad Skin Lighten and Brighten Eye Treatment was effective in lightening and brightening discolored under-eye skin by an average of 59%.
Significant improvement was detected through visual assessment of skin condition and corroborated by instrumental evaluation. Subjects reported a diminishing of under-eye bags and puffiness by up to 50%.

For press inquiries, please contact: Jennifer Newton | jnewton@murad.com

Murad has a Reasonable Basis For Claims That its Acne Complex® kit has a 90% success rate

Los Angeles, CA - February 16, 2005 - The Electronic Retailing Self-Regulation Program ("ERSP"), the electronic direct-response industry's self-regulatory program supervised by the National Advertising Review Council ("NARC"), announced that clinical skincare manufacturer Murad, Inc. provided a reasonable basis for its claim that the Murad Acne Complex® has a "90% success rate" at effectively treating acne conditions. The NARC also found that Murad’s tag line “Get Clear. Stay Clear™” for acne was reasonable in light of its effectiveness at treating acne and the visible factors of breakouts. Murad’s acne claims were successfully defended from attack by an unnamed competitor, which tried but failed to stop Murad from making its acne success rate claim. During the substantiation process, Murad provided ample support for the acne claim and established that it did indeed have a reasonable basis to claim such a success rate with its Acne Complex® kit.

"With millions of people affected by acne, it was my goal to create an easy, three-step system that would care for the varying skin types, clearing the acne without drying the skin," says Dr. Howard Murad, dermatologist, pharmacist, Associate Clinical Professor of Dermatology at UCLA, founder of Murad, and author of Wrinkle-Free Forever and the Cellulite Solution. With its innovative solutions for treating acne, Murad has sold over one million Acne Complex® Kits. The Acne Complex® Kit is a simple approach to attacking a complicated concern.

"Murad invests substantial resources in research, development and testing. We see the incredible success our products have on the consumer everyday from Dr. Murad’s patients, clients of the Murad Medical Spa and the many customers who write and tell us how much Murad has helped them. We never doubted that our acne claim could be supported" said Richard Murad, the company's Chief Operating Officer and General Counsel. “While we disagreed with the conclusions of the ERSP on certain non-acne related issues, we will take the recommendations of the ERSP into consideration in developing future advertising for Acne Complex. Overall we would encourage other companies to voluntarily submit to the process. It not only protect the interests of consumers, but also improves the industry standards for everyone."

Founded in 1989, Murad is the leading manufacturer of clinically based, doctor developed and scientifically proven skincare products. In addition to its topically applied selection of products targeted to address concerns from acne to aging, Murad is widely acknowledged as the founder and pioneer of Internal Skincare® the science of using nutritional supplements to improve the health of the skin. All Murad products incorporate the "Water Principle," an anti-aging theory discovered by Dr. Murad that promotes optimal skin health through the prevention of cellular water loss. Murad products are sold throughout the world at specialty retail locations and salons and spas. Murad products are also sold on its website http://www.murad.com.

For press inquiries, please contact:
Jennifer Newton | jnewton@murad.com

The signs may be slow and subtle or as forceful as a thunderstorm, no matter how it approaches, menopause is a fact of life for every woman.

An estimated 31.2 million women experienced menopause in the year 2000, compared with an estimated 28.7 million in 1990. Experts project that this figure will be as high as 50 million in 2020. As of the late 20th century, the life expectancy of women has increased to an average age of 81. This means that most women can expect to live over one third of their lives after menopause.

I’ve classified aging into three categories:

1. Intrinsic aging is considered the natural aging process. This is the aging process that would occur had we never been in the sun, never ingested toxins, never were exposed to pollutants, etc. Genetics play a key role in Intrinsic aging, if your parents aged well, odds are, you will also. In the skin, intrinsic aging results in loss of collagen and elastin, and reduced water content in the cells.

2. Extrinsic aging is also known as “Environmental Aging”, a term I introduced back in 1993. Extrinsic or Environmental Aging is the aging that results from the combination of external injury and compromised internal cellular functions. This is the type of aging that we can control. Factors such as sun exposure, smoking, stress, poor diet and intake of drugs or alcohol contribute to the aging process. Extrinsic aging effects can be reduced with preventative and corrective care. Signs of extrinsic aging are loss of collagen and elastin, hyperpigmentation, redness, dryness, thinner skin and loss of water in the cells.

3. Hormonal aging occurs as levels of estrogen decline. Low estrogen levels result in weakening of the collagen and elastin fibers. Skin becomes thinner and more fragile, with an increase in facial hair, and breakouts, with reduced water content in the cells.

In addition to the three types of aging described above, there are over three hundred theories on the causes of aging. At least a dozen explain why cells decline. No matter what the cause, free radical damage to inflammation, the net effect of all of them is water loss. Water is lost from within the cells. Water is lost from the material that keeps the collagen and elastin factories going. Water is lost from every layer of the skin.

Preventative and Long-Term Skin Care
Although there are no established rules for managing menopausal skin, proper skin care and lon-term preventative techniques can help lessen its visible influence.

Without treatment, skin after menopause will continue to degenerate. Estimates have indicted that skin loses up to 30% of its collagen in the first five years after menopause. Moreover, as skin thins by approximately a percentage point a year, the decelerated cell renewal rate leaves increasing numbers of dead skin cells on the surface.

Maintain balance with “The Water Principle”
I believe that the answer to caring for menopausal skin lies in the use of the anti-aging ingredient of the 21st century, WATER.

Having an internal and external skin care program (see sidebar) will help maintain the water balance in your entire body; I call it The Water Principle.

The Water Principle is not about drinking eight or more glasses of water a day, it’s about getting and maintaining water in the cells, so that the body can function in its full capacity.

The Water Principle is not about drinking eight or more glasses of water a day, it’s about getting and maintaining water in the cells, so that the body can function in its full capacity.

A skin care program for menopausal skin should consist of:

Antioxidants to disarm free radicals, which ultimately damage the cell membrane and cause it to lose water.

Anti-inflammatory agents to reduce inflammation, which releases free radicals that damage cellular structures and cause water loss.

Natural Moisture Factors to absorb water from the environment and act as a reservoir for water in the skin.

Hydrophobic Agents such as ceramides, which prevent water loss from all cells and maintain the skin’s barrier function – these can also be essential in repairing and maintaining cell membranes

Fatty Acid and Glucosamine supplements to encourage the body to make it’s own water-holding molecules

Lecithin and its building blocks, Phosphatidylcholine and Choline to maintain cell walls

Understanding Menopause

What is menopause and why is it so unsettling?
In a society that embraces youth, it signals the aging process and takes it’s toll emotionally as well as physically. A part of every woman’s reproductive life cycle, menopause is the cessation of menstruation during which a woman’s ovaries produce less of the female hormone estrogen. Menopause cannot be diagnosed medically, until a woman has been period-free for one year without being pregnant, breastfeeding, medication or certain diseases — factors that can also cause menstruation to cease. After menopause, women are no longer able to bear children and become more vulnerable to certain diseases.

Menopause is unpredictable. The drop in hormone levels differs from woman to woman, as do overall menopausal symptoms. While the onset of menopause usually occurs between the ages of 45 and 55, some women in their early 30’s experience menopausal sleeplessness, weight gain, irritability, temporary memory loss, hot flashes, increased facial hair, acne, and dry skin.

Medical studies have shown hormonal changes taking place during and post-menopause change skin composition. The subdermis, or layer of fat that cushions the skin, deflates while the production of collagen and elastin (structural protein tissue) lessens. The dermis (the skin’s supporting and nourishing layer) thins out and the skin loses much of its “extensibility,” or ability to bounce back. This is due primarily to the decreased level of estrogen that prevents the growth, leading to the weakening of blood vessels causing broken capillaries. The lack of nutrients and oxygen contribute to this thinning and slower cell turnover rate.

The physical ramifications of menopause are apparent. Wrinkles become more prominent, while the skin assumes a dull, discolored, rough, dry appearance. Additionally, women who never had acne in their life may discover unexpected breakouts because of a lack of estrogen in their bodies. They may find to have more facial hair and due to the thinning of skin with age, brown spots, more sensitive skin and fine, dilated blood vessels.

Skin Care in Menopausal Years

Hormone Replacement Therapy
An option for some women is Hormone Replacement Therapy (HRT), sometimes called postmenopausal hormone therapy. With HRT, estrogen is supplemented with another female hormone, progesterone. HRT is available in a variety of forms, such as estrogen tablets, patches, cream, implants or a combination of these. It is only suggested for healthy women with specific problems directly related to menopause. HRT has been shown to benefit in preventing many of the physical changes experienced during and after menopause. Side effects, however, to this therapy include monthly bleeding, breast tenderness, nausea, abdominal bloating and headaches. Recent studies warn women against the risks of HRT, it is important to thoroughly evaluate all benefits and risks with a physician.

Natural Ingredients and Formulas
Alternative methods to Hormone Replacement Therapy are also being used to relieve menopausal symptoms. Botanical and herbal products that mirror the effects of estrogen may provide some relief in alleviating menopausal symptoms, however again, it is important to discuss these option with your physician.
?With an increase of patients coming to me in the menopausal years, I’ve researched ingredients and formulas that are specifically designed address menopausal skin concerns. I’ve outlined key ingredients to look for:

Topically: Apricot Oil, Evening Primrose Oil and Borage Seed Oil protect the skin’s natural barrier, increasing moisture retention
Papaya enzymes gently exfoliate to reveal brighter, softer skin
Soy and Wild Yam Extracts, natural plant based estrogens
Clove Flower and Iris Extracts tone and firm skin
Glycosaminoglycans inhibit collagen breakdown
Shiitake Mushroom Extract conditions and firms skin
Shea Butter super hydrates to restore skin’s vibrancy
Chaparral Extract inhibits facial hair growth, clinically proven to reduce facial hair growth by 22% in 12 weeks

Internally:
Symptoms of menopause such as insomnia, irritability and joint pain may be addressed internally with natural solutions such as:
Melatonin to induce calm and encourage restful sleep
Glucosamine to boost collagen production and?ease joint pain
Biotin to strengthen hair, skin and nails
Essential Fatty Acids to hydrate from the inside out
B-complex Vitamins for overall health benefits

Inclusive Health
In addition to topically applied treatments and internal supplements, I recommend a program that also includes self-care or what I call, Inclusive Health™. Yes, you can reduce wrinkle, fight free radicals and inflammation and keep skin soft and pliable. But all of this rejuvenation is not enough if you’re not taking time to relax, de-stress, reduce isolation, and have passion in your life.

Skin and Overall Health
As you know, skin is the largest organ of our body. It not only signals touch and temperature, it detects nuances in our environment and communicates that to the brain. Harvard University researchers have dubbed this connection the nuero-immuno-cutaneous-endocrine network, or N.I.C.E.

Translated, everything that affects the skin, affects the body, and vice versa. The skin is connected to our brain, our nervous system, our hormones and our immune system. In broader terms, it’s a mind-skin link that reflects health as well as disease.

Spring is the perfect time of year to rejuvenate your skin. Prepare for the warm months ahead by pampering yourself with these Murad’s essentials!

Spring is the perfect time to re-think your basic skincare routine. As a practicing dermatologist, I’ve seen first-hand how the seasons can affect the health of our skin. With warmer weather on the horizon, preparing for increased sun exposure will help you rejuvenate dull winter skin and guard against future damage.

Treat yourself to a new spring skincare routine and rejuvenate your body with these five simple tips:

For a total body pick-up, try a revitalizing shower with Murad’s Exfoliating Body Cleansing Gel and finish up with our Vitamin C Energylift Lotion.

Gently buff away dull winter skin to reveal a soft and supple complexion. Use AHA/BHA Exfoliating Cleanser for a fresh new look.

Say goodbye to the turtlenecks! Firm your neck and decollate by using Night Reform every evening. To seal in moisture, follow up with Perfecting Serum.

Cold winter weather and dry indoor heat can rob your skin of essential moisture. Get your skin back on track with Murad’s Hydrating Gel Mask—the perfect way to revive your skin.

Relax and rejuvenate your mind and body with a Murad Professional Enzyme Treatment. This salon facial combines Papaya and Pineapple enzymes to exfoliate skin and deep clean pores for an incredible soft and healthy complexion.

Find a Murad salon near you

At Murad, our priority is to help you achieve beautiful skin and a feeling of total well being. We believe that when you look good, you feel good, and when your body is healthy, your appearance speaks for itself. So whether you use one product or a complete regimen, we guarantee that your skin will feel softer, younger and more beautiful than ever. That’s the Murad promise.

Summer can be a demanding time for your skin. Because intense heat and humidity may aggravate preexisting conditions or create new ones, it’s important to understand how to treat them. While summer skin problems are uncomfortable, you can easily control many of these dilemmas by altering your daily skin regimen and taking some simple precautions.

Back Acne
Often referred to as “bacne”, these breakouts can keep you from enjoying a summer day out. Get back on track with these easy-to-follow tips:

Tips
Wash your back immediately after exercising Make sure your back is completely dry before you dress Avoid wearing clothing that might irritate existing acne Apply sunscreen if your back is going to be exposed to the sun

Increased Pigmentation
If you spend time in the sun this summer, you may notice some increased skin pigmentation. This happens because the skin’s pigment, melanin, absorbs the energy of the sun’s harmful ultraviolet rays in order to protect the skin from overexposure. Skin tanning occurs as a result of this process, causing hyperpigmented areas to become even darker. Individuals with darker skin types are more commonly affected. Prevent it by:

Tips
Minimizing your exposure to sunlight can help prevent further darkening of existing hyperpigmented patches, as well as to prevent the formation of new ones. This is especially important for women who take birth control pills or hormone supplements and for people who have had hyperpigmentation in the past.
Using a sunscreen product with an SPF of at least 15 that protects against both UVA and UVB rays.
Taking anti-inflammatories and antioxidants to help your body fight sun damage

Rosacea
Rosacea looks like acne but it’s not. Rosacea occurs in the center of the face and begins with a red flush on the cheeks, chin, nose or forehead. The early stage is often mistaken for a mild skin irritation or sunburn, however left untreated, the redness can increase as tiny blood vessels may become visible. While it cannot be cured, the symptoms are reasonably well understood as are a variety of lifestyle factors that are known to trigger outbreaks in people that have the disease. Prevent outbreaks by:

Tips
Avoid sun exposure whenever possible
Use a high quality, non-irritating sunscreen every sing day, year round. Protect internally with antioxidant supplements and anti-inflammtories such as Ibuprofen
Stay in a cool, air-conditioned environment on hot, humid days
Show in cool, not hot water
Steer clear of foods that can inflame Rosacea. These include; hot spicy foods or beverages, alcohol, and daily products.
And of course, smoking should be avoided.

Summer Rash
Summer Rash - also known as Tinea Versicolor, is a common skin condition due to the overgrowth of yeast (a type of fungus). This overgrowth results in uneven skin color and scaling on the upper arms, chest, neck, and back areas. During the summer months when the temperature and humidity are high, the fungus can increase. This excess fungus on the skin prevents the normal pigmentation process and causes the spots to develop. It is easily treatable with topical and oral medications. Prevent it by:

Tips
Wash all body parts daily and use a dandruff shampoo Dry thoroughly, particularly between skin folds and between toes Avoid tight clothing, particularly in hot weather. Wear natural fabrics that will allow the skin to breathe. Change clothes daily, particularly footwear and undergarments.

Just as your body requires energy for an active lifestyle, your skin requires essential nutrients to keep its healthy appearance. It’s a fact that active skin ages faster than passive skin. If you’re spending time in the sun and you are not using a daily skincare regimen or sun care product, you’re probably stretching your skin to the limits.

It’s common knowledge that men and women differ in many ways. The way a man’s skin looks is primarily caused by differences that are hormonally conditioned. Men tend to have larger pores, as well as oilier and thicker skin than women. They are also less likely to put a lot of time into their skincare regimen.

The bottom line is that men and women have different skincare needs.

3 Simple Steps to Great Skin
Every man owes it to himself to take care of his health and youthful appearance. But taking good care of your skin doesn’t have to be time consuming or complicated. Think of these steps as your skin’s daily minimum requirement.

1. Cleanse

This may be the most important step you can take to ensure the health of your skin. Cleansers are designed to remove excess oil, dead skin cells, and dirt. A good one to try? Murad’s Clarifying Skin Cleanser removes 99.9% of bacteria within one minute while soothing skin and reducing acne breakouts.

2. Tone

Toners help remove traces of soap residue, surface skin cells and excess oil from your skin. They also remove dirt and perspiration from oilier skin types, and can tighten pores. Great for use as aftershave, Murad’s Clarifying Toner leaves your skin feeling cool, clean and refreshed.

3. Moisturize

Every skin type needs a moisturizer. Using one daily keeps your skin soft, smooth and well hydrated healthy. Try our Oil Free Skin Perfecting Lotion in the evening and our Age Proof Waterproof Sunblock SPF 30 for daytime protection. For an SPF and moisturizer in one, try Environmental Shield™ Essential Day Moisturizer SPF 15. This complete formula provides maximum moisturization during the day while repairing and protecting your skin from damage.

The Perfect Shave
Even in the best of circumstances, a daily shave can have an abrasive effect on your skin. The red bumps and skin irritations that often appear after shaving occur because minor nicks and cuts have been exposed to bacteria on your skin and traveled down into the hair follicle. This condition, called Folliculitis, is easily countered.
?Before shaving, use an antibacterial cleanser. This creates a smooth, clean canvas for shaving and prevents the typical inflammation around the hair follicle. After shaving, follow with a toner and at night, follow with an exfoliating treatment to help prevent clogged pores.
?Try the Acne Complex Kit™. A great all-in-one, easy to use system.

Skin cancer is the most common form of cancer in the United States with more than 1 million new cases diagnosed every year. Exposure to the sun is responsible for almost 90 percent of all skin cancers. Do you know what the early warning signs of skin cancer are? It’s more important than ever to be familiar with your skin so that you will be aware of any changes in moles, discolorations or sores that do not heal.

A represents Asymmetry.
Is half of your mole different from the other half?

B means Border.
Does the mole have an uneven, blurred or jagged edge?

C stands for Color.
Are there any variations in color (Tan, Brown, Red or Blue)?

D indicates Diameter.
Is the mole larger than a pencil eraser?

Facing the Facts
1 out of 7 people in the US will develop some form of skin cancer.

The sunburn you got 20 years ago can become skin cancer today

It only takes one serious sunburn to increase your risk of skin cancer as much as 50%

Skin cancer can occur anywhere on your body, but most common in places that are exposed to sunlight.

Choosing the Right Sunscreen
Before we learned about the dangers of ultraviolet light, soaking up the sun's rays used to be considered healthy. While you may like the look of “healthy” tan, it’s actually your body's attempt to protect itself from damage. According to the American Academy of Dermatology, frequent visits to tanning salons increase your exposure to ultraviolet radiation as well as your risk for skin cancer.

No matter what the season, incorporating a good sunscreen into your daily regimen will reduce the signs of premature aging and rescue your skin from serious skin damage. Because ordinary sunscreens only offer a basic barrier against the sun, you may still experience inflammation, dryness, and even some skin damage.

To keep your skin soft and healthy all year long, be sure to look for a sunscreen that has the following ingredients:

Already burned?
If your skin has felt the ravages of the sun, taking immediate action will help your skin heal more quickly. Sunburn should be treated for the healing of current sunburn pain, skin damage and potential skin cancer as well as to prevent further sunburn.

1. Use Aloe Vera

A wonderfully treatment, this soothing gel should be applied to the affected areas of the skin to soothe and rehydrate the dried and damaged surfaces.

2. Moisturize

A general skin moisturizer can be applied to burned areas to cool and soothe painful or itchy areas.

3. Add Vitamin’s to your Skin’s Diet

Vitamin E can be taken regularly as part of a daily supplement or spread as salve on sunburned areas. Vitamin C, another powerful antioxidant, will help prevent severe damage as well as shorten the effects of any damage that may have occurred.

Sun Protection in Tablet Form!
Topical sunscreens provide us with the ability to enjoy the outdoors. However, in our hurry to get outdoors, we often forget to apply protection to delicate skin areas, which leads to damaging sunburns.

Imagine being protected from the inside out—no more forgotten skin areas or messy lotions. It’s very possible that in the near future, we will be able to take a small capsule and protect every square inch of skin. An exciting new study has shown that when, potent antioxidants called polyphenols are taken internally, they can increase the SPF (sun protection factor) of topical sunscreens by up to 25%! Pomegranate extract has the highest levels of polyphenols found in any food substance and provides powerful antioxidant protection against the signs of premature aging. It is currently available in tablet form and has been proven to safely enhance your topical sun protection by up to 25%.

As we look towards the future, the concept of an oral sunscreen may be the next step in optimal sun protection. Stay tuned to discover how your skin can stay young, healthy, and sun damage free!